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Cod liver oil during pregnancy A population-based case control study was performed in Norway that included 85 children with type 1 diabetes and 1,071 randomly selected children without diabetes. When [...]

The acute effects of second-hand cigarette smoke (also known as 'passive smoking') on coronary artery circulation was determined (using coronary flow velocity reserve [CVFR], assessed by Doppler echocardiography) in 30 [...]

In a multicenter case-control study of 750 patients with vascular disease of the coronary, cerebral, or peripheral vessels and 800 control subjects, elevation of total homocysteine (tHcy) (above the 80th [...]

Data on thyroid status, aortic atherosclerosis, and history of myocardial infarction were obtained at baseline in a random sample of 1,149 women (mean age, 69 years) participating in the Rotterdam [...]

The Arterial Disease Multiple Intervention Trial, a multicenter randomized, placebo-controlled trial, examined the effect of niacin compared with placebo on homocyst(e)ine(Hcy) levels in 52 individuals (mean age, 68 years) with [...]

One hundred-one patients (mean age, 53 years) with multiple risk factors for atherosclerosis, most of whom also had clinically manifest atherosclerosis, were treated daily with folic acid (2.5 mg), pyridoxine [...]

Six children (aged 10-13 years) with steroid-responsive idiopathic nephrotic syndrome were studied. Prednisone was discontinued and a hypoallergenic elemental diet was given. After proteinuria had decreased to 500 mg per [...]

Six hundred twenty-eight Japanese patients (mean age, 71 years) with residual hemiplegia at least one year after their first ischemic stroke were randomly assigned to receive, in double-blind fashion, 5 [...]

The author of this report has found amebas of the genus Naegleria in synovial tissue and other tissues of patients with rheumatoid disease. These amebas have also been found to [...]

Eleven patients with diabetes participated in a crossover study (2 weeks on each of 2 different diets), and 13 other patients with diabetes participated in a 6-week randomized trial of [...]

Osteoporosis affects as many as 30% of post-menopausal women and about 5% of older men in the United States. More than 1.2 million fractures (primarily of the hip, spine or [...]

A meta-analysis of 19 vitamin E studies, scheduled to be published in January 2005 in The Annals of Internal Medicine, concluded that high-dose vitamin E supplementation (400 IU per day [...]

One hundred eighty-six people considered at high risk for deep vein thrombosis (DVT) who were undergoing a seven- to eight-hour plane flight were randomly assigned to receive Flite Tabs (Aidan, [...]

In a cross-sectional study of 1,226 people (aged 18-65 years) living in Pizarra, Spain, the presence of excess concentrations of polar compounds (defined as > 20%) in home cooking oil [...]

Fifty patients (mean age, 60 years) with carotid intimamedia thickness (IMT) ≥ 1 mm, which is associated with an increased risk of cerebral ischemia, were randomly assigned to receive daily, [...]

Two hundred-ten consecutive patients with chronic sinusitis, of whom 101 were treated surgically, were studied. Fungal cultures of nasal secretions were positive in 202 (96%) of the patients. Candida albicans [...]

Some 3,994 patients aged 55 years or older with vascular disease or diabetes were randomly assigned to receive, in double-blind fashion, 400 IU/day of vitamin E (RRR-alpha-tocopheryl acetate) or placebo [...]

One hundred-forty healthy pregnant women hospitalized for delivery and their newborn infants were studied. The presence of cotinine in urine and serum was used to classify mothers as smokers (n [...]

Two hundred seventy-seven children (aged 3 years) living on the Isle of Wight, UK, consumed a diet for four weeks that eliminated artificial colorings and benzoate preservatives. During the second [...]

Two hundred ninety-eight healthy postmenopausal women (mean age, 50 years) were randomly assigned to receive, in double-blind fashion, tablets providing 150 mg/day of soy isoflavones or placebo for 5 years. [...]

Twenty patients (aged 18-45 years) with chronic active inflammatory bowel disease (7 with Crohn's disease, 13 with ulcerative colitis) who had failed to respond to various medications were treated with [...]

Twenty-five patients with end-stage renal disease who had symptoms of restless legs syndrome (RLS) were randomly assigned to receive, in double-blind fashion, a single intravenous infusion of iron dextran (1,000 [...]

One hundred seventy-three patients with somatization disorder, undifferentiated somatoform disorder, or somatoform autonomic dysfunction, but not major depression, were randomly assigned to receive, in double-blind fashion, 300 mg of St. [...]

The association between use of vitamin supplements during the first six months of life and risk of developing asthma or food allergies during early childhood was assessed in a prospective [...]

One hundred-ten obese men (body mass index of 30 or greater) aged 35 to 55 years, without diabetes, hypertension, or hyperlipidemia, who had erectile dysfunction (defined as a score of [...]

Tadpoles of four species of frogs were exposed for 30 days at early and late developmental stages to low concentrations of the pesticide atrazine (3, 30, or 100 ppb; the [...]

The association between dietary intakes of choline and its metabolite betaine (as determined by a food-frequency questionnaires) and the risk of neural-tube defects (NTDs) was assessed in a case-control study [...]

In this review article, the author points out that high intake of caffeine can produce symptoms that are indistinguishable from those of anxiety neurosis, such as nervousness, irritability, tremulousness, occasional [...]

The enzyme 5-lipoxygenase catalyzes the conversion of arachidonic acid to leukotrienes, which are involved in the inflammatory process. Chronic inflammation is believed to play an important role in the development [...]

Fine-needle aspiration cytology of the thyroid gland was performed on 219 patients complaining of fatigue of more than one year's duration. Eighty-seven patients (40%) were found to have definite histological [...]

A population-based sample of 32,200 Scottish children was studied at age 39-42 months. The prevalence of obesity (defined as body mass index [BMI] at or above the 95th percentile) was [...]

Seventy-six patients who had experienced a myocardial infarction before age 45 (mean age, 39 years) were studied. Fourteen of these patients (18%) had increased levels of circulating immune complexes (CICs) [...]

During the hydrogenation of phylloquinone (vitamin K1) rich oils (such as soybean and canola oil), phylloquinone is converted to its hydrogenated form, dihydrophylloquinone. The mean intake of dihydrophylloquinone by US [...]

Six hundred-eighty children with frequent episodes of acute otitis media (mean, 8.3 episodes per year) were studied. The mean hemoglobin concentration was significantly lower in these children than in 200 [...]