1. Reactivity of Dinuclear Copper(II) Complexes with N-Salicylidene Glycine Schiff Bases as Carboxylesterase Models.
- Author
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Xu, Bin, Jiang, Weidong, Liu, Fuan, Yu, Yongde, and Dong, Juan
- Subjects
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METAL complexes , *COPPER compounds , *SALICYLIDENE aniline , *GLYCINE , *SCHIFF bases , *CARBOXYLESTERASES - Abstract
ABSTRACT Two phenoxo-bridged dinuclear copper(II) complexes (Cu2L12, Cu2L22) with N-salicylidene glycine Schiff bases were prepared and evaluated their performance for catalyzing the hydrolysis of p-nitrophenyl picolinate (PNPP). The observations reveal that the as-prepared dinuclear copper(II) complexes exhibited better activity by two to three orders of magnitude rate enhancement in comparison with the autohydrolysis rate of PNPP. Chloro-containing Cu2L22 aroused approximately three times kinetic advantage over chloro-free Cu2L12 at pH 7.0, which is probably contributed to the electron-withdrawing inductive effect of the 5′-chloride group. Moreover, it was found that the pH-responded kinetic behavior displayed an enzyme-like property for the PNPP hydrolysis by the two complexes. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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