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Abstract The aim of this retrospective study was to evaluate the efficiency and safety of total body irradiation plus cyclophosphamide (TBI/Cy) followed by autogenetic hematopoietic stem cell transplantation (auto-HSCT) in T-LBL/ALL patients that cannot receive allogeneic hematopoietic stem cell transplant (allo-HSCT). Between 2013 and 2023, 24 patients received auto-HSCT following by TBI/Cy, 26 patients underwent allo-HSCT, all patients achieved completed hematopoietic reconstitution after HSCT. The progression free survival (PFS) and overall survival (OS) had no statistically significant differences between the two groups (P = 0.791, HR 1.127, 95%CI 0.456–2.785; P = 0.456, HR 0.685, 95%CI 0.256–1.828). Although the cumulative incidence of relapse was lower for patients who received allo-HSCT than auto-HSCT (P = 0.033, HR 3.707, 95%CI 1.188–11.570, 2-year relapse 11.5% vs. 33.3%), the incidence of non-relapse mortality (NRM) was higher than that in the auto-HSCT group (P = 0.014, HR 0.000, 95%CI -1.000 - -1.000, 2-year NRM, 23.1% vs. 0%). Trough Landmark analysis, the two groups showed a statistically significant difference in 3-year PFS and 4-year OS curves (Figure S2A&B, P = 0.039, HR 0.426, 95%CI 0.163–1.117; P = 0.014, HR 0.317, 95%CI 0.113–0.887). By COX analysis, poor baseline performance status (ECOG-PS ≥ 2) and CNS involvement were risk factors for PFS and OS. In conclusion, TBI/Cy followed by auto-HSCT is a good choice next to allo-HSCT for patients with T-LBL/ALL.

The Ozone Monitoring Suite-Nadir (OMS-N) instrument is the first hyperspectral remote sensor in the ultraviolet band of China’s Fengyun series satellites. It can be used to detect several kinds of atmospheric constituents. This paper describes the prelaunch spectral calibration of the OMS-N onboard FengYun 3F. Several critical spectral parameters including the spectral resolution, spectral dispersion, and the instrument spectral response function were determined through laser-based measurements. A secondary peak of the instrument spectral response function from the short wavelength side of the ultraviolet band was found, and the possible influence on data applications was analyzed using a reference solar model and radiative transfer model. The results indicate that the spectral resolution and spectral accuracy of OMS-N meet the mission requirements. However, the asymmetries in the instrument spectral response function in the ultraviolet band were found near nadir rows, which are expressed as the “asymmetric central peak” and “secondary peak”. The analysis results show that if the influences of the instrument spectral response function “asymmetric central peak” and “secondary peak” in the ultraviolet band are ignored, they will bring an error as large as 5% at the center of the absorption line.

This paper presents the prelaunch radiometric calibration of the Ozone Monitor Suite-Nadir (OMS-N) instrument, a vital payload on the FY-3F satellite. FY-3F achieved a successful launch on 3 August 2023. The radiance calibration of the OMS-N instrument was achieved using an integrating sphere, with known exit radiance ascertained through a transferring radiometer. The calibration model incorporates six energy levels. The Solar Simulator Standard System was employed to validate the calibration results, selecting specific rows to represent varying spatial dimensions. Considering the influence of xenon lamp characteristic peaks and transmission errors during the calibration process, the average deviation remained within 2.3% for the VIS channel, 3% for the UV1 channel, and 2.2% for the UV2 channel. Furthermore, the uncertainty of the radiometric calibration was analyzed. The results indicated an absolute uncertainty of 2.33% for both the UV1 and UV2 channels and 1.69% for the VIS channel. The relative uncertainty was 1.84% for both the UV1 and UV2 channels and 1.45% for the VIS channel. The obtained calibration coefficients are accurate and reliable and can be used for the inversion of product parameters, which is of great significance to the quantitative application of satellite data and the advancement of scientific research on quantitative remote sensing.

The Absorbing Aerosol Sensor (AAS) is carried on the Gao-Fen 5B (GF-5B) satellite, and it allows for the measurement of solar backscatter radiation by the atmosphere in the UV–Vis bands. The AAS is an imaging spectrometer that employs CCD for capturing both a continuous spectrum and the cross-track orientation with a 114° wide swath. The broad field of view provides daily global envelopment with a 4 km spatial resolution at the nadir. This paper mainly analyzes the initial working status of the instrument in orbit, including wavelength calibration, radiometric calibration, detector performance, and product availability. Preliminary observations indicate the ability of the AAS to monitor absorbing aerosols like dust, biomass burning, volcano ash, and some pollution aerosols and to identify the aerosol events in China and other regions with high spatial resolution.