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Autoimmune thyroiditis (AIT) is characterised by infiltration of lymphocytes and destruction of thyroid gland. It results from the interaction of genetic predisposition and environmental triggers. Among environmental factors some infections, medications and inadequate micronutrients supply like selenium (Se) deficiency are believed to play a role., Aim: The aim of our study was to assess the serum selenium concentration in patients with AIT and healthy volunteers in the Polish population living in the Poznan district, and to compare our results with similar trials conducted on other European AIT groups., Materials and Methods: Fifty three patients with AIT were included in the study. Elevated thyroperoxidase antibodies and/or thyroglobulin antibodies concentration and abnormalities typical for AIT in the thyroid ultrasound were the inclusion criteria. A control group consisted of 36 healthy, age and sex-matched volunteers., Results: The median Se concentration was 56.67 μg/L in the AIT group and 39.75 μg/L in the controls (p>0.05). Decreased Se concentration was observed in 62% of the patients and in 72% of the controls (p=0.47). There was no statistically significant difference in Se status in AIT group when compared to the other Polish, German, Austrian, Dutch and Greek populations with AIT. Significantly higher values were observed in Italian and Greek study when compared to present results in AIT group., Conclusions: No association between selenium status and prevalence of autoimmune thyroiditis in Polish population living in Poznan district was noticed. Nevertheless determination of the normal serum Se concentration for European populations is necessary. Further studies with enlarged studied groups should be implemented., (© 2018 MEDPRESS.)

Background: Agaricus bisporus (white button mushroom) is an important culinary and medicinal species of worldwide importance. The present study investigated for the first time whether it may be grown on substrates supplemented with Se alone or in combination with Cu and/or Zn (0.1-0.8 mmol L -1 ) to produce fruiting bodies of increased nutritional value., Results: As found, substrate supplementation did not affect yielded biomass up to 0.6 mmol L -1 element concentrations regardless of the cultivation model. At 0.8 mmol L -1 Se + Cu and Se + Zn supplementation biomass comparable with controls still developed. The accumulation of trace elements in the fruiting bodies generally increased over the concentration gradient reaching its maximum at 0.6 mmol L -1 (for Se + Zn and Se + Cu + Zn) and 0.8 mmol L -1 (for Se and Se + Cu). The organic Se constituted the greatest share in total Se quota. As calculated, each 10 g of dried fruiting bodies of A. bisporus obtained from 0.6 or 0.8 mmol L -1 supplementation would represent 342-469% of the Recommended Daily Allowance (RDA) for Se, 43.4-48.5% for Cu and 5.2-5.8% for Zn., Conclusion: Considering inexpensive methods of A. bisporus cultivation, global popularity and use of this mushroom, its biofortification with Se, Cu and Zn could have a practical application in deficiency prevention and assisted treatment. © 2016 Society of Chemical Industry., (© 2016 Society of Chemical Industry.)

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The aim of the study was to evaluate the possibility of supplementation with inorganic forms of selenium (Na2SeO4and Na2SeO3) in concentrations of 0, 0.1, 0.2, 0.4, 0.6, 0.8, 1.0 and 1.5 mM of three medicinal mushroom species:Agrocybe aegerita,Hericium erinaceusandGanoderma lucidum. Tested mushroom species grew in Se additions of 0–0.6 mM (A. aegeritaandH. erinaceus), while growth ofG. lucidumbodies was observed for 0–0.8 mM. For the latter mushroom species, the total Se content was the highest. Content of Seorgwas diverse; for control bodies it was the highest forG. lucidum(only organic forms were present), lower forA. aegerita(84% organic forms) and the lowest forH. erinaceus(56% organic forms). Accumulation of Se(IV) was generally significantly higher than Se(VI) for all tested mushroom species. There was no significant decrease ofA. aegeritaorG. lucidumbiomass with the exception ofG. lucidumbodies growing under 0.8 mM of Se species addition (15.51 ± 6.53 g). Biomass ofH. erinaceusbodies was the highest under 0.2 (197.04 ± 8.73 g), control (191.80 ± 6.06 g) and 0.1 mM (185.04 ± 8.73 g) of both inorganic salts. The addition to the medium of Se salts brought about macroscopic changes in the fruiting bodies of the examined mushrooms. Concentrations exceeding 0.4 mM caused diminution of carpophores or even their total absence. In addition, colour changes of fruiting bodies were also recorded. At Se concentrations of 0.4 and 0.6 mM,A. aegeritafruiting bodies were distinctly lighter and those ofH. erinaceuschanged colour from purely white to white-pink. [ABSTRACT FROM PUBLISHER]

Highlights: [•] The study of the influence of tsunami deposits on the environment has been provided. [•] The potential release of deposit components to the environment has been shown. [•] The mechanism of changes in content of selected components of tsunami deposit have been shown. [•] The description of this mechanism has been proposed. [•] A pioneer approach to the study of post-depositional changes of metalloids content in deposits. [ABSTRACT FROM AUTHOR]

The objective of the study was to determine total phenolic and flavonoid content and composition as well as antioxidant activity in Pholiota nameko , Pleurotus eryngii and Pleurotus ostreatus growing on substrates supplemented with selenium salts. The concentration of Se in control samples (without Se addition) was 4.86 ± 0.12 mg/kg for P. nameko , 2.54 ± 0.22 mg/kg DW for P. ostreatus , and 7.34 ± 0.17 mg/kg DW for P. eryngii . The addition of selenium salts to the substrate resulted in increases of Se concentration in the fruiting bodies. Total phenolic and flavonoid concentration was the highest for P. nameko . In all examined mushrooms p-hydroxybenzoic, p-coumaric and ferulic acids and myricetin were identified, while gallic and t-cinnamic acids were identified only in P. nameko . The greatest inhibition of DPPH and ABTS radicals was confirmed for P. nameko , and the lowest for P. eryngii . Se supplementation at the concentration between 0.5 and 5.0 mmol/L inhibited growth of fruiting bodies of the mushrooms and enhanced the biosynthesis of phenolics and flavonoids. The increase of scavenging activity for all mushrooms was confirmed in Se-treated mushrooms. The inhibition of DPPH and ABTS radicals was correlated with total phenolic and flavonoid contents only for P. ostreatus . [ABSTRACT FROM AUTHOR]