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Background and Hypotheses A wealth of evidence suggests that adolescent psychotic experiences (PEs), and especially auditory hallucinations (AHs), are associated with an increased risk for self-injurious behavior (SIB). However, the directionality and specificity of this association are not well understood, and there are no published studies investigating within-person effects over time. The present study aimed to test whether AHs and SIB prospectively increase reciprocal risk at the individual level during early-to-middle adolescence. Study Design Three waves (12y, 14y, and 16y) of self-reported AHs and SIB data from a large Tokyo-based adolescent birth cohort (N = 2825) were used. Random Intercept Cross-Lagged Panel Model (RI-CLPM) analysis was conducted to test the within-person prospective associations between AHs and SIB. Study Results At the within-person level, AHs were associated with subsequent SIB over the observation period (12y–14y: β =.118, P <.001; 14–16y: β =.086, P =.012). The reverse SIB->AHs relationship was non-significant at 12–14y (β =.047, P =.112) but emerged from 14y to 16y as the primary direction of influence (β =.243, P <.001). Incorporating depression as a time-varying covariate did not meaningfully alter model estimates. Conclusions A complex bi-directional pattern of relationships was observed between AHs and SIB over the measurement period, and these relationships were independent of depressive symptoms. Adolescent AHs may be both a predictor of later SIB and also a manifestation of SIB-induced psychological distress. [ABSTRACT FROM AUTHOR]

AbstractObjectiveMethodResultsConclusions\nHIGHLIGHTSBullying has consistently been highlighted as a risk factor for youth self-harm. Less is known about associations by bullying sub-type (i.e., physical, verbal, relational, cyberbullying), among boys and girls in diverse urban populations. This study aimed to explore: (1) prevalence of bullying and lifetime self-harm; (2) cross-sectional associations between bullying and self-harm. Both aims investigated bullying sub-types and the role of sex.Baseline data on bullying victimization and lifetime self-harm were drawn from REACH (Resilience, Ethnicity and AdolesCent Mental Health), an accelerated cohort study of adolescent mental health in London, United Kingdom. Data on baseline self-harm and sex were available for 3,060 adolescents aged 11–14 years (Mage=12.4, 50.6% girls, >80% ethnic minority groups) from 10 schools.Prevalence of bullying in the past six months was 22.3% and lifetime self-harm was 16.9%. Both were more common in girls than boys (adjusted risk ratios: bullying, 1.13 [1.02,1.25]; self-harm, 1.45 [1.03,1.86]). By bullying sub-type, prevalence estimates ranged from 4.1% (cyberbullying) to 16.6% (physical bullying). Bullying was associated with self-harm (aRR 3.35 [2.89,3.82]) for both girls (aRR 3.61 [3.07,4.14]) and boys (aRR 2.96 [2.27,3.65]), independent of sex, age, free school meals and ethnic group. All sub-types were associated with self-harm (aRRs 3.16–4.34), for girls and boys.These baseline findings underline the importance of exploring nuances between bullying sub-types and self-harm, by sex or gender.Bullying strongly associated with self-harm in a diverse, urban sample of adolescentsAssociations strong for boys and girls, across all bullying sub-typesFuture research should further explore nuances by sex, and experiences for cis-gender youthBullying strongly associated with self-harm in a diverse, urban sample of adolescentsAssociations strong for boys and girls, across all bullying sub-typesFuture research should further explore nuances by sex, and experiences for cis-gender youth [ABSTRACT FROM AUTHOR]

There is a well-documented epidemiological association between auditory hallucinations and self-harm in the general population. However, there has been limited research examining specific characteristics of auditory hallucinations (e.g., type, source, or context of voices) as correlates of self-harm. We used prospective data from the Tokyo Teen Cohort to explore whether characteristics of voices reported at age 14 were differentially associated with self-harm behaviors at ages 14 and 16. Among respondents with auditory hallucinations, respondents who experienced voices that "said something bad" about them or commented on their thoughts and actions were most likely to report concurrent self-harm, whereas positive or praising voices were protective. Negative voices continued to predict self-harm two years later, at age 16, even with adjustment for self-harm at age 14. The age of the voices, source of the voices, and context (e.g., falling asleep or while sick) was not associated with likelihood of reporting concurrent or subsequent self-harm behaviors. Assessing for negative voices in particular, rather than auditory hallucinations or psychotic experiences more broadly, may provide a more specific indicator of risk for self-harm among adolescents. The real-world utility of these epidemiological findings should be further examined in clinical settings. [ABSTRACT FROM AUTHOR]