New data on Zygaenidae from French Guiana are provided together with a checklist and key to genera and species. Seven species are newly described: Pampa hermieri (Tarmann & Drouet), new species, Pampa pseudovenata (Tarmann & Drouet), new species, Stylura guyanensis (Tarmann & Drouet), new species, Monalita faurei (Tarmann & Drouet), new species, Monalita laguerrei (Tarmann & Drouet), new species, Seryda gallardi (Tarmann & Drouet), new species, and Seryda confusa (Tarmann & Drouet), new species. All species are discussed in detail and their habitus and genitalia are figured. A key to the narrow-winged genera of American Zygaenidae and all species of French Guiana is provided. [ABSTRACT FROM AUTHOR]