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Copyright of Regional Science Policy & Practice is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Regional Science Policy & Practice is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

• A dynamic model structure was designed to delineate spatiotemporal evolution of health disparities. • The paper analyzed racial disparities in human mobility and COVID-19 health outcomes jointly. • Confounding effects from built environment, socioeconomics, demographics, and partisanship on racial disparities have been quantified. • The study found a persistent and disproportionate burden of COVID-19 suffered by racial minorities. Social distancing has become a key countermeasure to contain the dissemination of COVID-19. This study examined county-level racial/ethnic disparities in human mobility and COVID-19 health outcomes during the year 2020 by leveraging geo-tracking data across the contiguous US. Sets of generalized additive models were fitted under cross-sectional and time-varying settings, with percentage of mobility change, percentage of staying home, COVID-19 infection rate, and case-fatality ratio as dependent variables, respectively. After adjusting for spatial effects, built environment, socioeconomics, demographics, and partisanship, we found counties with higher Asian populations decreased most in travel, counties with higher White and Asian populations experienced the least infection rate, and counties with higher African American populations presented the highest case-fatality ratio. Control variables, particularly partisanship and education attainment, significantly influenced modeling results. Time-varying analyses further suggested racial differences in human mobility varied dramatically at the beginning but remained stable during the pandemic, while racial differences in COVID-19 outcomes broadly decreased over time. All conclusions hold robust with different aggregation units or model specifications. Altogether, our analyses shine a spotlight on the entrenched racial segregation in the US as well as how it may influence the mobility patterns, urban forms, and health disparities during the COVID-19. [ABSTRACT FROM AUTHOR]

• A big-data-driven analytical framework assessing human mobility during COVID-19. • Location-based evidence from large-scale and privacy-protected samples in the US. • County-level human mobility metrics are made publicly available via an open platform. • Comprehensive assessment of human mobility using generalized additive mixed models. • The policy effect of "Stay-at-home" order on restricting travel is found limited. During the unprecedented coronavirus disease 2019 (COVID-19) challenge, non-pharmaceutical interventions became a widely adopted strategy to limit physical movements and interactions to mitigate virus transmissions. For situational awareness and decision-support, quickly available yet accurate big-data analytics about human mobility and social distancing is invaluable to agencies and decision-makers. This paper presents a big-data-driven analytical framework that ingests terabytes of data on a daily basis and quantitatively assesses the human mobility trend during COVID-19. Using mobile device location data of over 150 million monthly active samples in the United States (U.S.), the study successfully measures human mobility with three main metrics at the county level: daily average number of trips per person; daily average person-miles traveled; and daily percentage of residents staying home. A set of generalized additive mixed models is employed to disentangle the policy effect on human mobility from other confounding effects including virus effect, socio-demographic effect, weather effect, industry effect, and spatiotemporal autocorrelation. Results reveal the policy plays a limited, time-decreasing, and region-specific effect on human movement. The stay-at-home orders only contribute to a 3.5%-7.9% decrease in human mobility, while the reopening guidelines lead to a 1.6%-5.2% mobility increase. Results also indicate a reasonable spatial heterogeneity among the U.S. counties, wherein the number of confirmed COVID-19 cases, income levels, industry structure, age and racial distribution play important roles. The data informatics generated by the framework are made available to the public for a timely understanding of mobility trends and policy effects, as well as for time-sensitive decision support to further contain the spread of the virus. [ABSTRACT FROM AUTHOR]