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Your search keyword '"beta-Thalassemia radiotherapy"' showing total 5 results
Start Over Descriptor "beta-Thalassemia radiotherapy" Topic spinal cord compression
5 results on '"beta-Thalassemia radiotherapy"'

1. Extramedullary Hematopoiesis Spinal Cord Compression in Beta-thalassemia: Role of Reirradiation as a Challenging Therapeutic Approach in Recurrent Disease.

Author

Bennassi A, Debbi K, Bernard G, and Belkacemi Y

Subjects
Humans, Male, Recurrence, Female, Adult, beta-Thalassemia complications, beta-Thalassemia therapy, beta-Thalassemia radiotherapy, Hematopoiesis, Extramedullary, Spinal Cord Compression radiotherapy, Spinal Cord Compression etiology, Re-Irradiation methods
Abstract

Competing Interests: Disclosures None.

Published
2024
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3. Complete recovery from paraparesis in spinal cord compression due to extramedullary haemopoiesis in beta-thalassaemia by emergency radiation therapy.

Author

Ruo Redda MG, Allis S, Reali A, Bartoncini S, Roggero S, Anglesio SM, and Piga A

Subjects
Humans, Prognosis, Hematopoiesis, Extramedullary radiation effects, Paraparesis etiology, Paraparesis physiopathology, Paraparesis radiotherapy, Recovery of Function, Spinal Cord Compression complications, Spinal Cord Compression physiopathology, Spinal Cord Compression radiotherapy, beta-Thalassemia complications, beta-Thalassemia physiopathology, beta-Thalassemia radiotherapy
Abstract

Extramedullary haemopoiesis (EMH) is a complication commonly associated with beta-thalassaemia intermedia; it is frequently asymptomatic but can sometimes lead to symptomatic tumour-like masses. No guidelines or common consensus are available in literature regarding the different treatment strategies and only single cases have been reported. We describe a case of spinal cord compression due to intrathoracic EMH masses treated with combined radiotherapy and hydroxyurea., (© 2014 The Authors; Internal Medicine Journal © 2014 Royal Australasian College of Physicians.)

Published
2014
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4. Extramedullary hematopoiesis and paraplegia in a patient with hemoglobin e-Beta thalassemia.

Author

Alam MR, Habib MS, Dhakal GP, Khan MR, Rahim MA, Chowdhury AJ, and Mahmud TK

Subjects
Adult, Humans, Male, Paraplegia etiology, Spinal Cord Compression etiology, beta-Thalassemia complications, Hematopoiesis, Extramedullary, Hemoglobin E, Paraplegia radiotherapy, Spinal Cord Compression radiotherapy, beta-Thalassemia radiotherapy
Abstract

Extramedullary hematopoiesis (EMH) occurs in patients with various hematologic disorders involving a chronic increase in the production of red blood cells, and is often associated polycythemia vera and sickle cell anaemia, but is less common with thalassemia especially with hemoglobin E-beta thalassemia. Spinal cord compression due to EMH is a extremely rare complication of thalassemia and may present with paraparesis or paraplegia with or without sensory impairment. Treatment options mostly include surgery and/or radiotherapy. Whereas cases presenting with paraplegia have been treated with either surgery or radiotherapy with equal frequency and efficacy, almost all reported cases with paraplegia have been treated with surgery with or without radiation therapy. We hereby report a case of hemoglobin E-beta thalassemia with paraplegia treated successfully with radiotherapy.

Published
2010

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