1. Effects of perioperative clinical hypnosis on heart rate variability in patients undergoing oncologic surgery: secondary outcomes of a randomized controlled trial.
- Author
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Azam, Muhammad Abid, Weinrib, Aliza Z., Slepian, P. Maxwell, Rosenbloom, Brittany N., Waisman, Anna, Clarke, Hance, and Katz, Joel
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TUMOR surgery ,SECONDARY analysis ,ACADEMIC medical centers ,MORPHINE ,CAUSAL models ,DATA analysis ,STATISTICAL sampling ,PROBABILITY theory ,QUESTIONNAIRES ,CANCER patients ,DESCRIPTIVE statistics ,HEART beat ,HYPNOTISM ,PAIN management ,PAIN ,RESEARCH methodology ,STATISTICS ,DATA analysis software ,COMPARATIVE studies ,PERIOPERATIVE care ,RELAXATION for health ,REGRESSION analysis - Abstract
Introduction: Clinical hypnosis has been proposed for post-surgical pain management for its potential vagal-mediated anti-inflammatory properties. Evidence is needed to understand its effectiveness for post-surgical recovery. Iin this secondary outcome study, it was hypothesized that surgical oncology patients randomized to receive perioperative clinical hypnosis (CH) would demonstrate greater heart-rate variability (HRV) during rest and relaxation at a 1-month post-surgery assessment compared to a treatment-as-usual group (TAU). Methods: After REB approval, trial registration and informed consent, 92 participants were randomized to receive CH (n = 45) or TAU (n = 47). CH participants received a CH session before surgery and during post-surgical inhospital stay HRV was assessed during rest (5 min) and relaxation (10 min) before and 1-month after surgery. Pain intensity was obtained using a 0-10 numeric rating scale pre and post 1-week and 1-month post surgery. Results: One month after surgery, HRV was significantly higher in CH group (n = 29) during rest and relaxation (both p < 0.05, d = 0.73) than TAU group (n = 28). By contrast, rest and relaxation HRV decreased from pre- to 1-month post-surgery for the TAU (both p < 0.001, d > 0.48) but not the CH group. Pain intensity increased from pre-surgery to 1-week post-surgery (p < 0.001, d = 0.50), and decreased from 1-week to 1-month post-surgery (p = 0.005, d = 0.21) for all participants. Discussion: The results suggest that hypnosis prevents the deleterious effects of surgery on HRV by preserving pre-operative vagal activity. These findings underscore the potential of clinical hypnosis in mitigating the adverse effects of surgery on autonomic function and may have significant implications for enhancing post-surgical recovery and pain management strategies. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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