10 results on '"Wei, Xuan"'
Search Results
2. Forecasting the rate of hand injuries in Singapore.
- Author
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Glen, Liau Zi Qiang, Wong, Joel Yat Seng, Tay, Wei Xuan, Weng, Jiayi, Cox, Gregory, and Cheah, Andre Eu Jin
- Subjects
STATISTICS ,HAND injuries ,MANUFACTURING industries ,MULTIPLE regression analysis ,HAND surgery ,TERTIARY care ,FORECASTING ,ELECTRONIC health records ,DATA analysis software - Abstract
Purpose: This study aims to analyse the correlation between the incidence rate of hand injuries and various major economic indicators in Singapore. We hypothesise that the number of hand injuries is correlated to activity in the construction and manufacturing industries in Singapore. Methods: Twenty thousand seven hundred sixty-four patients who underwent hand surgeries in a tertiary institution between 2012 to 2018 were reviewed. Two independent, blinded observers extracted the frequency of hand surgeries performed from Electronic Medical Records. Economic indicators pertinent to Singapore's economic activity were collected and smoothed by simple moving average of the prior 3 months. Results were analysed using IBM SPSS v25.0. Results: Significant independent univariate variables were Purchasing-Manager-Index and Industrial-Production-Index. Multiple linear regression of quarterly reported figures showed that Total-Livestock-Slaughtered, Total-Seafood-Handled, Purchasing-Manger-Index, Industrial-Production-Index, Gas-Tariffs, Construction-Index, Consumer-Price-Index, Total-Air-Cargo-Handled, Total-Container-Throughput, Total-Road-Traffic-Accident-Casualties, Food-&-Beverage-Services-Index were significantly correlated (p < 0.05) with hand injuries, with R
2 = 62.3%. Conclusion: Quarterly economic indicators from major economic industries can be used to predict the incidence of hand injuries with a 62.3% correlation. These findings may be useful for anticipating healthcare resource allocation to treat hand injuries. Type of study and level of evidence: Economic and decision, Level II. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
3. Comparison of neutrophil to lymphocyte ratio and prognostic nutritional index with other clinical and molecular biomarkers for prediction of glioblastoma multiforme outcome
- Author
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Kieran F. Scott, David A. Lynch, Joseph W. Po, Celine Garrett, Therese M. Becker, Wei Xuan, and Paul de Souza
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Male ,Oncology ,Multivariate analysis ,Neutrophils ,Cancer Treatment ,Kaplan-Meier Estimate ,Biochemistry ,Dexamethasone ,Mathematical and Statistical Techniques ,Surgical oncology ,Medicine and Health Sciences ,Lymphocytes ,Immune Response ,Neurological Tumors ,Multidisciplinary ,medicine.diagnostic_test ,Brain Neoplasms ,Statistics ,Middle Aged ,Tumor Resection ,Prognosis ,Isocitrate Dehydrogenase ,Progression-Free Survival ,Surgical Oncology ,Neurology ,Physical Sciences ,Medicine ,Female ,Research Article ,medicine.drug ,Clinical Oncology ,medicine.medical_specialty ,Blastoma ,Science ,Immunology ,Nutritional Status ,Surgical and Invasive Medical Procedures ,Research and Analysis Methods ,Signs and Symptoms ,Internal medicine ,Biopsy ,Biomarkers, Tumor ,medicine ,Humans ,Progression-free survival ,Statistical Methods ,Neutrophil to lymphocyte ratio ,Survival analysis ,Aged ,Retrospective Studies ,Inflammation ,Surgical Resection ,business.industry ,Biology and Life Sciences ,Cancers and Neoplasms ,Log-rank test ,Multivariate Analysis ,Mutation ,Clinical Medicine ,Glioblastoma ,business ,Mathematics ,Biomarkers ,Glioblastoma Multiforme - Abstract
Objective Pre- and post-operative neutrophil to lymphocyte ratio (NLR) and prognostic nutritional index (PNI) and other prognostic clinicopathological variables were correlated with progression free survival (PFS) and overall survival (OS) of Glioblastoma Multiforme (GBM) patients. Methods GBM patients (n = 87, single-centre, recruited 2013–2019) were retrospectively divided into low and high groups using literature-derived cut-offs (NLR = 5.07, PNI = 46.97). Kaplan-Meier survival curves and log rank tests assessed PFS and OS. Univariate and multivariate analyses identified PFS and OS prognosticators. Results High vs low post-operative PNI cohort was associated with longer PFS (279 vs 136 days, p = 0.009), but significance was lost on multivariate analysis. Post-operative ECOG (p = 0.043), daily dexamethasone (p = 0.023) and IDH mutation (p = 0.046) were significant on multivariate analysis for PFS. High pre- and post-operative PNI were associated with improved OS (384 vs 114 days, p = 0.034 and 516 vs 245 days, p = 0.001, respectively). Low postoperative NLR correlated with OS (408 vs 249 days, p = 0.029). On multivariate analysis using forward selection process, extent of resection (EOR) (GTR vs biopsy, p = 0.004 and STR vs biopsy, p = 0.011), and any previous surgery (p = 0.014) were independent prognostic biomarkers for OS. On multivariate analysis of these latter variables with literature-derived prognostic biomarkers, EOR remained significantly associated with OS (p = 0.037). Conclusions EOR, followed by having any surgery prior to GBM, are the most significant independent predictors of GBM patient’s OS. Post-operative ECOG, daily dexamethasone and IDH mutation are independent prognostic biomarkers for PFS. PNI may be superior to NLR. Post- vs pre-operative serum inflammatory marker levels may be associated with survival.
- Published
- 2021
4. Predictive Value of Fasting Blood Glucose for Microvascular Obstruction in Nondiabetic Patients with ST-Segment Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention.
- Author
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Wu, Han, Li, Ran, Wang, Kun, Mu, Dan, Chen, Jian-Zhou, Wei, Xuan, Bao, Xue, Wei, Zhong-Hai, Xie, Jun, and Xu, Biao
- Subjects
BLOOD sugar ,MAGNETIC resonance imaging ,MICROCIRCULATION ,MYOCARDIAL infarction ,STATISTICS ,THROMBOLYTIC therapy ,PREPROCEDURAL fasting ,PERCUTANEOUS coronary intervention ,VENTRICULAR ejection fraction - Abstract
Background. The relationship between fasting blood glucose (FBG) and microvascular obstruction (MVO) after primary percutaneous coronary intervention (PCI) remains unclear in nondiabetic patients with ST-segment elevation myocardial infarction (STEMI). This study aimed to determine the predictive value of FBG in MVO in nondiabetic STEMI patients. Methods. A total of 108 nondiabetic STEMI patients undergoing primary PCI were enrolled in this study. The patients were classified into either the MVO group or non-MVO group based on cardiac magnetic resonance imaging (CMR). Results. FBG in the MVO group was higher than in the non-MVO group. Univariate analysis showed that FBG, peak high-sensitive troponin T (TnT), pre-PCI thrombolysis in myocardial infarction (pre-PCI TIMI) flow, left ventricular ejection fraction (LVEF), infarction size, left ventricular end-diastolic diameter (LVEDd), left ventricular end-diastolic volume (LVEDV), and global longitudinal strain (GLS) were likely predictive factors of MVO. After adjustment for other parameters, FBG, peak TnT, LVEF, and LVEDV remained independent predictors for MVO. Conclusion. FBG was independently associated with MVO in nondiabetic STEMI patients. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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5. The distribution of probability values in medical abstracts: an observational study
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Wei Xuan, Ian A. Harris, Abhinav Aggarwal, and Bastiaan Ginsel
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Systematic error ,Abstracting and Indexing ,MEDLINE ,p value ,Publication bias ,General Biochemistry, Genetics and Molecular Biology ,Statistics ,Chi-square test ,Medicine ,Humans ,p-value ,Probability ,Medicine(all) ,Chi-Square Distribution ,business.industry ,Biochemistry, Genetics and Molecular Biology(all) ,General Medicine ,Distribution (mathematics) ,Open Access Publishing ,p-hacking ,Observational study ,High incidence ,business ,Chi-squared distribution ,Research Article - Abstract
Background A relatively high incidence of p values immediately below 0.05 (such as 0.047 or 0.04) compared to p values immediately above 0.05 (such as 0.051 or 0.06) has been noticed anecdotally in published medical abstracts. If p values immediately below 0.05 are over-represented, such a distribution may reflect the true underlying distribution of p values or may be due to error (a false distribution). If due to error, a consistent over-representation of p values immediately below 0.05 would be a systematic error due either to publication bias or (overt or inadvertent) bias within studies. Methods We searched the Medline 2012 database to identify abstracts containing a p value. Two thousand abstracts out of 80,649 abstracts were randomly selected. Two independent researchers extracted all p values. The p values were plotted and compared to a predicted curve. Chi square test was used to test assumptions and significance was set at 0.05. Results 2798 p value ranges and 3236 exact p values were reported. 4973 of these (82 %) were significant (
- Published
- 2015
6. Usage Analysis of University of Manitoba Licensed Databases via EZproxy's Logs.
- Author
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Wei Xuan
- Subjects
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INFORMATION technology , *UNIFORM Resource Locators , *DATABASES , *STATISTICS - Abstract
Compared to vendor-provided data, Transaction Log Analysis (TLA) can provide unique benefits to a library in analyzing database usage. Meanwhile, it also requires librarians to have a broad knowledge of Information Technology in order to implement a TLA. This article will present an in-house database system developed at the University of Manitoba Libraries to analyze EZProxy's Starting Point Uniform Resource Locator logs. The database visits that happened in the past two years have been imported into this system and are split into two categories, on-campus and offcampus visits. Unique statistical information from each category is also discussed. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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7. Influence of shoe midsole hardness on plantar pressure distribution in four basketball-related movements.
- Author
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Lam, Wing-Kai, Ng, Wei Xuan, and Kong, Pui Wah
- Subjects
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FOOT physiology , *ANTHROPOMETRY , *ATHLETIC shoes , *BASKETBALL , *BIOPHYSICS , *CLINICAL trials , *COLLEGE athletes , *CROSSOVER trials , *EXERCISE physiology , *JUMPING , *KINEMATICS , *MOTOR ability , *PROBABILITY theory , *RUNNING , *STATISTICAL sampling , *SCIENTIFIC apparatus & instruments , *STATISTICS , *VIDEO recording , *PRODUCT design , *DATA analysis , *EFFECT sizes (Statistics) , *RANDOMIZED controlled trials , *DATA analysis software , *DESCRIPTIVE statistics - Abstract
This study examined how shoe midsole hardness influenced plantar pressure in basketball-related movements. Twenty male university basketball players wore customized shoes with hard and soft midsoles (60 and 50 Shore C) to perform four movements: running, maximal forward sprinting, maximal 45° cutting and lay-up. Plantar loading was recorded using an in-shoe pressure measuring system, with peak pressure (PP) and pressure time integral (PTI) extracted from 10 plantar regions. Compared with hard shoes, subjects exhibited lower PP in one or more plantar regions when wearing the soft shoes across all tested movements (Ps < 0.05). Lower PTI was also observed in the hallux for 45° cutting, and the toes and forefoot regions during the first step of lay-up in the soft shoe condition (Ps < 0.05). In conclusion, using a softer midsole in the forefoot region may be a plausible remedy to reduce the high plantar loading experienced by basketball players. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
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8. Calculating the Sample Size
- Author
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Jennifer Peat, Katrina Williams, Craig Mellis, and Wei Xuan
- Subjects
business.industry ,Sample size determination ,Statistics ,Medicine ,business - Published
- 2002
9. Clinical trial of a pollen filter for reducing seasonal rhinitis
- Author
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Euan R. Tovey, Helen K. Reddel, T.J. O'Meara, J.K. Sercombe, Geoffrey G. Morgan, and Wei Xuan
- Subjects
Clinical trial ,Veterinary medicine ,Filter (video) ,business.industry ,Pollen ,Immunology ,Statistics ,Immunology and Allergy ,Medicine ,Seasonal Rhinitis ,business ,medicine.disease_cause - Published
- 2003
10. Convolutional neural network assistance significantly improves dermatologists' diagnosis of cutaneous tumours using clinical images.
- Author
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Ba, Wei, Wu, Huan, Chen, Wei W., Wang, Shu H., Zhang, Zi Y., Wei, Xuan J., Wang, Wen J., Yang, Lei, Zhou, Dong M., Zhuang, Yi X., Zhong, Qin, Song, Zhi G., and Li, Cheng X.
- Subjects
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DERMATOLOGISTS , *STATISTICS , *WORK , *PHYSICIANS' attitudes , *SKIN tumors , *DIAGNOSTIC imaging , *EXPERIENTIAL learning , *DESCRIPTIVE statistics , *ARTIFICIAL neural networks , *STATISTICAL sampling , *SENSITIVITY & specificity (Statistics) - Abstract
Convolutional neural networks (CNNs) have demonstrated expert-level performance in cutaneous tumour classification using clinical images, but most previous studies have focused on dermatologist-versus-CNN comparisons rather than their combination. The objective of our study was to evaluate the potential impact of CNN assistance on dermatologists for clinical image interpretation. A multi-class CNN was trained and validated using a dataset of 25,773 clinical images comprising 10 categories of cutaneous tumours. The CNN's performance was tested on an independent dataset of 2107 images. A total of 400 images (40 per category) were randomly selected from the test dataset. A fully crossed, self-control, multi-reader multi-case (MRMC) study was conducted to compare the performance of 18 board-certified dermatologists (experience: 13/18 ≤ 10 years; 5/18>10 years) in interpreting the 400 clinical images with or without CNN assistance. The CNN achieved an overall accuracy of 78.45% and kappa of 0.73 in the classification of 10 types of cutaneous tumours on 2107 images. CNN-assisted dermatologists achieved a higher accuracy (76.60% vs. 62.78%, P < 0.001) and kappa (0.74 vs. 0.59, P < 0.001) than unassisted dermatologists in interpreting the 400 clinical images. Dermatologists with less experience benefited more from CNN assistance. At the binary classification level (malignant or benign), the sensitivity (89.56% vs. 83.21%, P < 0.001) and specificity (87.90% vs. 80.92%, P < 0.001) of dermatologists with CNN assistance were also significantly improved than those without. CNN assistance improved dermatologist accuracy in interpreting cutaneous tumours and could further boost the acceptance of this new technique. • A multi-class CNN was developed using 25,773 clinical images. • An MRMC study was conducted to evaluate performance of CNN-assisted dermatologists. • CNN-assisted dermatologists achieved a higher accuracy and kappa than unassisted. • Dermatologists with less experience benefited more from CNN assistance. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
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