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Bayesian methods are useful for statistical inference. However, real-world problems can be challenging using Bayesian methods when the data analyst has only limited prior knowledge. In this paper we consider a class of problems, called Partial Bayes problems, in which the prior information is only partially available. Taking the recently proposed Inferential Model approach, we develop a general inference framework for Partial Bayes problems, and derive both exact and efficient solutions. In addition to the theoretical investigation, numerical results and real applications are used to demonstrate the superior performance of the proposed method.

The Behrens-Fisher problem is a well-known hypothesis testing problem in statistics concerning two-sample mean comparison. In this article, we confirm one conjecture in Eaton and Olshen (1972), which provides stochastic bounds for the multivariate Behrens-Fisher test statistic under the null hypothesis. We also extend their results on the stochastic ordering of random quotients to the arbitrary finite dimensional case. This work can also be seen as a generalization of Hsu (1938) that provided the bounds for the univariate Behrens-Fisher problem. The results obtained in this article can be used to derive a testing procedure for the multivariate Behrens-Fisher problem that strongly controls the Type I error.

Motivated by the analysis of nonnegative data objects, a novel Nested Nonnegative Cone Analysis (NNCA) approach is proposed to overcome some drawbacks of existing methods. The application of traditional PCA/SVD method to nonnegative data often cause the approximation matrix leave the nonnegative cone, which leads to non-interpretable and sometimes nonsensical results. The nonnegative matrix factorization (NMF) approach overcomes this issue, however the NMF approximation matrices suffer several drawbacks: 1) the factorization may not be unique, 2) the resulting approximation matrix at a specific rank may not be unique, and 3) the subspaces spanned by the approximation matrices at different ranks may not be nested. These drawbacks will cause troubles in determining the number of components and in multi-scale (in ranks) interpretability. The NNCA approach proposed in this paper naturally generates a nested structure, and is shown to be unique at each rank. Simulations are used in this paper to illustrate the drawbacks of the traditional methods, and the usefulness of the NNCA method., Comment: 18 pages, 3 figures

A novel multi-resolution cluster detection (MCD) method is proposed to identify irregularly shaped clusters in space. Multi-scale test statistic on a single cell is derived based on likelihood ratio statistic for Bernoulli sequence, Poisson sequence and Normal sequence. A neighborhood variability measure is defined to select the optimal test threshold. The MCD method is compared with single scale testing methods controlling for false discovery rate and the spatial scan statistics using simulation and f-MRI data. The MCD method is shown to be more effective for discovering irregularly shaped clusters, and the implementation of this method does not require heavy computation, making it suitable for cluster detection for large spatial data.