1. Centrantheroside F, a new ionone glycoside from Centranthera grandiflora
- Author
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Wei-Lie Xiao, Xing-Jie Zhang, Yan-Mei Ning, Xin-Xin Liang, Ruihan Zhang, Qi Li, Hui-Juan Li, and Xiao-Li Li
- Subjects
Pharmacology ,chemistry.chemical_classification ,Circular dichroism ,biology ,Chemistry ,Stereochemistry ,Scrophulariaceae ,Organic Chemistry ,Absolute configuration ,Pharmaceutical Science ,Glycoside ,General Medicine ,biology.organism_classification ,Ionone ,Analytical Chemistry ,Nitric oxide ,chemistry.chemical_compound ,Complementary and alternative medicine ,Drug Discovery ,Molecular Medicine - Abstract
One new ionone glycoside, named centrantheroside F (1), together with 9 known compounds (2-10), were isolated from the roots of Centranthera grandiflora. Their structures were determined by spectroscopic data analyses and comparing with the literature data. The absolute configuration of 1 was confirmed via 2 D NMR and electronic circular dichroism (ECD). All isolated compounds were evaluated for their inhibitory activity on lipopolysaccharide (LPS)-induced nitric oxide (NO) production. more...
- Published
- 2021
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