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1. Synthesis, in vivo antileukemic evaluation and comparative study of novel 5alpha-7-keto steroidal esters of chlorambucil and its active metabolite.

2. Rational design, synthesis, and in vivo evaluation of the antileukemic activity of six new alkylating steroidal esters.

3. Structure-antileukemic activity relationship study of B- and D-ring modified and nonmodified steroidal esters of 4-methyl-3-N,N-bis(2-chloroethyl)amino benzoic acid: a comparative study.

4. Rational design, synthesis and in vitro evaluation of three new alkylating steroidal esters.

5. Structure-anti-leukemic activity relationship study of B- and D-ring modified and non-modified steroidal esters of chlorambucil's active metabolite.

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