1. A near-infrared AIE fluorescent probe for accurate detection of sulfur dioxide derivatives and visualization of fingerprints.
- Author
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Sun, Saidong, Xue, Ke, Zhao, Yongfei, and Qi, Zhengjian
- Subjects
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FLUORESCENT probes , *INTRAMOLECULAR proton transfer reactions , *FORENSIC fingerprinting , *DATA visualization , *CELL imaging , *STOKES shift - Abstract
In most biophysiological processes, sulfur dioxide (SO 2) is an important intracellular signaling molecule that plays an important role. The change of SO 2 in cells are closely related to various diseases such as neurological disorders and lung cancer, so it is necessary to develop fluorescent probes with the ability to accurately detect SO 2 during physiological processes. In this work, we designed and synthesized a multifunctional fluorescent probe TIS. TIS has excellent properties such as near-infrared emission, large stokes shift, excellent SO 2 detection capabilities, low detection limit, high specificity and visualization of color change before and after reaction. Simultaneously, TIS has low cytotoxicity, good biocompatibility, clear cell imaging capability and mitochondrial targeting ability. In addition, the ability of TIS to be applied to different material surfaces for latent fingerprint fluorescence imaging was also explored. TIS provides an excellent method for the accurate detection of SO 2 derivatives and shows great potential applications in near-infrared cellular imaging and latent fingerprint fluorescence imaging. (a) TIS response mechanisms for HSO 3 −. (b) application of TIS. [Display omitted] • A NIR emission fluorescent probe with AIE characterization. • TIS has long emission wavelength (795 nm) and large Stokes shift (265 nm). • Dual detection channel for SO 2 derivatives accurate detection. • Superior colocalization effect on mitochondrial (0.86). • Clear three-level finger imaging capability. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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