1. Power spectral density-based resting-state EEG classification of first-episode psychosis.
- Author
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Redwan, Sadi Md., Uddin, Md Palash, Ulhaq, Anwaar, Sharif, Muhammad Imran, and Krishnamoorthy, Govind
- Subjects
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ELECTROENCEPHALOGRAPHY , *SUPPORT vector machines , *PSYCHOSES , *MACHINE learning , *GAUSSIAN processes , *FEATURE extraction - Abstract
Historically, the analysis of stimulus-dependent time–frequency patterns has been the cornerstone of most electroencephalography (EEG) studies. The abnormal oscillations in high-frequency waves associated with psychotic disorders during sensory and cognitive tasks have been studied many times. However, any significant dissimilarity in the resting-state low-frequency bands is yet to be established. Spectral analysis of the alpha and delta band waves shows the effectiveness of stimulus-independent EEG in identifying the abnormal activity patterns of pathological brains. A generalized model incorporating multiple frequency bands should be more efficient in associating potential EEG biomarkers with first-episode psychosis (FEP), leading to an accurate diagnosis. We explore multiple machine-learning methods, including random-forest, support vector machine, and Gaussian process classifier (GPC), to demonstrate the practicality of resting-state power spectral density (PSD) to distinguish patients of FEP from healthy controls. A comprehensive discussion of our preprocessing methods for PSD analysis and a detailed comparison of different models are included in this paper. The GPC model outperforms the other models with a specificity of 95.78% to show that PSD can be used as an effective feature extraction technique for analyzing and classifying resting-state EEG signals of psychiatric disorders. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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