11 results on '"Badia, Josep M."'
Search Results
2. An interventional nationwide surveillance program lowers postoperative infection rates in elective colorectal surgery. A cohort study (2008-2019)
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Arroyo-García, Nares, Badia, Josep M., Vázquez, Ana, Pera Roman, Miguel, Parés, David, Limón, Enric, Almendral, Alexander, Piriz, Marta, Cecilia, Díez, Fraccalvieri, Domenico, López Contreras, Joaquín, Pujol, Miquel, Colorectal Surveillance Team, VINCat Program, Arroyo-García, Nares, Badia, Josep M., Vázquez, Ana, Pera Roman, Miguel, Parés, David, Limón, Enric, Almendral, Alexander, Piriz, Marta, Cecilia, Díez, Fraccalvieri, Domenico, López Contreras, Joaquín Pujol, Miquel, Colorectal Surveillance Team, VINCat Program, [Arroyo-Garcia N, Badia JM] Department of Surgery, Hospital General Granollers, Granollers, Spain. School of Medicine, Universitat Internacional de Catalunya, Barcelona, Spain. [Vázquez A] Servei d’Estadística Aplicada, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Pera M] Department of Surgery, Hospital del Mar, Barcelona, Spain. [Parés D] Department of Surgery, Hospital Universitari Germans Trias i Pujol, Badalona, Spain. [Limón E] VINCat Program, Universitat de Barcelona, Barcelona, Spain, and Hospital General de Granollers
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Prevenció i control ,Infeccions quirúrgiques ,Cirurgia colorectal ,Surgical wound infection ,Estudios de cohortes ,Infection control ,Còlon - Cirurgia ,Cohort Studies ,Health Occupations::Medicine::Specialties, Surgical::Colorectal Surgery [DISCIPLINES AND OCCUPATIONS] ,Cirugía colorrectal ,Control d'infeccions ,Prevención y control ,Colorectal surgery ,Risk Factors ,Infección del sitio quirúrgico ,Humans ,Surgical Wound Infection ,Estudis de cohorts ,Epidemiologia ,Proporción de infección estandarizada ,Digestive System Surgical Procedures ,Standardized infection ratio ,Infecció del lloc quirúrgic ,Adverse effects ,Prevention & control ,Infeccions quirúrgiques - Estudi de casos ,Cirurgia colorrectal ,General Medicine ,Efectos adversos ,Infección de la herida quirúrgica ,Elective Surgical Procedures ,profesiones sanitarias::medicina::especialidades quirúrgicas::cirugía colorrectal [DISCIPLINAS Y OCUPACIONES] ,Ratio d'infecció estandarditzat ,Surgery ,Efectes adversos ,Colorectal Surgery ,Surgical site infection ,Infecció de ferides quirúrgiques - Abstract
Colorectal surgery; Postoperative infection; Cohort studies Cirugía colorrectal; Infección postoperatoria; Estudios de cohortes Cirurgia colorectal; Infecció postoperatòria; Estudis de cohorts Background: Colorectal surgery is associated with the highest rate of surgical site infection (SSI). This study analyses the effectiveness of an interventional surveillance program on SSI rates after elective colorectal surgery. Material and methods: Cohort study showing temporal trends of SSI rates and Standardized Infection Ratio (SIR) in elective colorectal surgery over a 12-year period. Prospectively collected data of a national SSI surveillance program was analysed and the effect of specific interventions was evaluated. Patient and procedure characteristics, as well as SIR and SSI rates were stratified by risk categories and type of SSI analysed using stepwise multivariate logistic regression models. Results: In a cohort of 42,330 operations, overall cumulative SSI incidence was 16.31%, and organ-space SSI (O/S-SSI) was 8.59%. There was a 61.63% relative decrease in SSI rates (rho = -0.95804). The intervention which achieved the greatest SSI reduction was a bundle of 6 measures. SSI in pre-bundle period was 19.73% vs. 11.10% in post-bundle period (OR 1.969; IC 95% 1.860-2.085; p < 0.0001). O/S-SSI were 9.08% vs. 6.06%, respectively (OR 1.547; IC 95% 1.433-1.670; p < 0.0001). Median length of stay was 7 days, with a significant decrease over the studied period (rho = -0.98414). Mortality of the series was 1.08%, ranging from 0.35% to 2.0%, but a highly significant decrease was observed (rho = -0.67133). Conclusions: Detailed analysis of risk factors and postoperative infection in colorectal surgery allows strategies for reducing SSI incidence to be designed. An interventional surveillance program has been effective in decreasing SIR and SSI rates.
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- 2021
3. Leveraging a nationwide infection surveillance program to implement a colorectal surgical site infection reduction bundle: a pragmatic, prospective, and multicenter cohort study.
- Author
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Badia, Josep M., Arroyo-Garcia, Nares, Vázquez, Ana, Almendral, Alexander, Gomila-Grange, Aina, Fraccalvieri, Domenico, Parés, David, Abad-Torrent, Ana, Pascual, Marta, Solís-Peña, Alejandro, Puig-Asensio, Mireia, Pera, Miguel, Gudiol, Francesc, Limón, Enric, and Pujol, Miquel
- Abstract
Background: Bundled interventions usually reduce surgical site infection (SSI) when implemented at single hospitals, but the feasibility of their implementation at the nationwide level and their clinical results are not well established. Materials and Methods: Pragmatic interventional study to analyze the implementation and outcomes of a colorectal surgery care bundle within a nationwide quality improvement program. The bundle consisted of antibiotic prophylaxis, oral antibiotic prophylaxis (OAP), mechanical bowel preparation, laparoscopy, normothermia, and a wound retractor. Control group (CG) and Intervention group (IG) were compared. Overall SSI, superficial (S-SSI), deep (D-SSI), and organ/space (O/S-SSI) rates were analyzed. Secondary endpoints included microbiology, 30-day mortality, and length of hospital stay. Results: A total of 37 849 procedures were included, 19 655 in the CG and 18 194 in the IG. In all, 5462 SSIs (14.43%) were detected: 1767 S-SSI (4.67%), 847 D-SSI (2.24%), and 2838 O/S-SSI (7.5%). Overall SSI fell from 18.38% (CG) to 10.17% (IG), odds ratio (OR) of 0.503 [0.473-0.524]. O/S-SSI rates were 9.15% (CG) and 5.72% (IG), OR of 0.602 [0.556-0.652]. The overall SSI rate was 16.71% when no measure was applied and 6.23% when all six were used. Bundle implementation reduced the probability of overall SSI (OR: 0.331; CI95: 0.242-0.453), and also O/S-SSI rate (OR: 0.643; CI95: 0.416-0.919). In the univariate analysis, all measures except normothermia were associated with a reduction in overall SSI, while only laparoscopy, OAP, and mechanical bowel preparation were related to a decrease in O/S-SSI. Laparoscopy, wound retractor, and OAP decreased overall SSI and O/S-SSI in the multivariate analysis. Conclusions: In this cohort study, the application of a specific care bundle within a nationwide nosocomial infection surveillance system proved feasible and resulted in a significant reduction in overall and O/S-SSI rates in the elective colon and rectal surgery. The OR for SSI fell between 1.5 and 3 times after the implementation of the bundle. [ABSTRACT FROM AUTHOR]
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- 2023
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- View/download PDF
4. The persistent breach between evidence and practice in the prevention of surgical site infection. Qualitative study
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Badia, Josep M, Rubio-Pérez, Inés, López-Menéndez, José, Diez, Cecilia, Al-Raies Bolaños, Bader, Ocaña-Guaita, Julia, Meijome, Xose M, Chamorro-Pons, Manuel, Calderón-Nájera, Ramón, Ortega-Pérez, Gloria, Paredes-Esteban, Rosa, Sánchez-Viguera, Cristina, Vilallonga, Ramon, Picardo, Antonio L, Bravo-Brañas, Elena, Espin, Eloy, Balibrea, José M, and Spanish Observatory of Surgical Infection
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Prevenció i control ,medicine.medical_specialty ,Glucose control ,Preventive measures ,Surgical wound infection ,Preventative measures ,Antiseptic solutions ,Antisepsis ,03 medical and health sciences ,0302 clinical medicine ,Prevención y control ,Infección del sitio quirúrgico ,medicine ,Surgical Wound Infection ,Humans ,Antibiotic prophylaxis ,Therapeutic Irrigation ,Enquestes i qüestionaris ,Qualitative Research ,Actual use ,Infecció del lloc quirúrgic ,business.industry ,Chlorhexidine ,Mesures preventives ,General Medicine ,Perioperative ,Antibiotic Prophylaxis ,Medidas preventivas ,Prevention and control ,Infección de la herida quirúrgica ,Encuestas y cuestionarios ,030220 oncology & carcinogenesis ,Practice Guidelines as Topic ,Emergency medicine ,030211 gastroenterology & hepatology ,Surgery ,Infecció de la ferida quirúrgica ,Surveys and questionnaires ,business ,Surgical site infection ,medicine.drug ,Qualitative research - Abstract
Background: Despite the dissemination of guidelines for surgical site infection (SSI) prevention, a gap between the theoretical measures and their compliance persists. Accurate estimates of the implementation of preventative measures is crucial before planning dissemination strategies. Methods: A web-based survey was distributed to members of 11 Associations of operative nurses and surgeons. Questions aimed to determine their awareness of evidence, personal beliefs and actual use of the main preventative measures. Results: Of 1105 responders, 50.5% receive no feed-back of their SSI rate. Responders show a moderate rate of awareness of the recommendations about not removing hair, hair clipping, skin antisepsis with alcoholic solutions, and normothermia. Antibiotic prophylaxis is given for more than 24 h by 18.8% of respondents. Screening for S. aureus is performed by 27.6%. Hair removal by shaving is used by 16.6% of responders. The most common antiseptic solutions are alcoholic chlorhexidine (57.2%) and aqueous povidone (23.3%). 62.8% of surgeons allow the solution to air dry before applying surgical drapes. Adhesive drapes in the surgical field are used routinely in 33.4% of cases. Perioperative normothermia, glucose control and hyperoxia are used in 84.3%, 65.9% and 23.3% of cases. Antimicrobial sutures and negative pressure therapy are used by 20.2% and 43.5% of teams, respectively. Prior to closing the incision, 83.9% replace surgical instruments always or selectively. Wound irrigation before closing is used in 78.1% of cases, mostly with saline. Check-lists, standardized orders, surveillance, feed-back and educational programs were rated most highly by respondents as a means to improve compliance with preventative guidelines, but few of these strategies were in place at their institutions. Conclusion: Gaps in the translation of evidence into practice remain in the prevention of SSI among different surgical specialities. Several areas for improvement have been identified, as some core prevention measures are not in common use. info:eu-repo/semantics/publishedVersion
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- 2020
5. Resumen ejecutivo del Documento de Consenso de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC) y de la Asociación Española de Cirujanos (AEC) en profilaxis antibiótica en cirugía
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Toro López, M. Dolores del, Arias Díaz, Javier, Balibrea, José M., Benito, Natividad, Canut Blasco, Andrés, Esteve, Erika, Horcajada, Juan Pablo, Ruiz Mesa, Juan Diego, Manuel Vázquez, Alba, Muñoz Casares, Cristóbal, Pozo, Jose Luis del, Pujol, Miquel, Riera, Melchor, Jimeno, Jaime, Rubio Pérez, Inés, Ruiz Tovar Polo, Jaime, Serrablo, Alejandro, Soriano, Alex, Badia, Josep M., Grupo de Estudio de PA de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC), and Asociación Española de Cirujanos (AEC)
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medicine.medical_specialty ,Prevención de la infección ,Antibiòtics ,030230 surgery ,Rational use ,Profilaxis antibiótica ,03 medical and health sciences ,0302 clinical medicine ,Antibiotic resistance ,Medicina preventiva ,Surgical procedures ,Antibiotics ,Infection prevention ,Procedimientos quirúrgicos ,medicine ,Operacions quirúrgiques ,Antibiotic prophylaxis ,Elective surgery ,Intensive care medicine ,Preventive medicine ,business.industry ,Clinical microbiology ,Infección de localización quirúrgica ,Surgical operations ,Surgery ,business ,Surgical site infection - Abstract
[ES] La profilaxis antibiótica en cirugía es una de las medidas más eficaces para la prevención de la infección de localización quirúrgica, aunque su uso es con frecuencia inadecuado, pudiendo incrementar el riesgo de infección, toxicidades y resistencias bacterianas. Debido al avance en las técnicas quirúrgicas y la emergencia de microorganismos multirresistentes las actuales pautas de profilaxis precisan ser revisadas. La Sociedad Española de Enfermedades Infecciosas (SEIMC), conjuntamente con la Asociación Española de Cirujanos (AEC) ha revisado y actualizado las recomendaciones de profilaxis antimicrobiana para adaptarlas a cada tipo de intervención quirúrgica y a la epidemiología actual. En este documento se recogen las recomendaciones de los antimicrobianos utilizados en profilaxis en los diferentes procedimientos, las dosis, la duración, la profilaxis en huéspedes especiales, y en situación epidemiológica de multirresistencia, de tal forma que permitan un manejo estandarizado, un uso racional, seguro y efectivo de los mismos en la cirugía electiva., [EN] Antibiotic prophylaxis in surgery is one of the most effective measures for preventing surgical site infection, although its use is frequently inadequate and may even increase the risk of infection, toxicities and antimicrobial resistance. As a result of advances in surgical techniques and the emergence of multidrug-resistant organisms, the current guidelines for prophylaxis need to be revised. The Sociedad Española de Enfermedades Infecciosas (Spanish Society of Infectious Diseases and Clinical Microbiology) (SEIMC) together with the Asociación Española de Cirujanos (Spanish Association of Surgeons) (AEC) have revised and updated the recommendations for antibiotic prophylaxis in surgery to adapt them to any type of surgical intervention and to current epidemiology. This document gathers together the recommendations on antimicrobial prophylaxis in the various procedures, with doses, duration, prophylaxis in special patient groups, and in epidemiological settings of multidrug resistance to facilitate standardized management and the safe, effective and rational use of antibiotics in elective surgery.
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- 2021
6. Executive summary of the Consensus Document of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and of the Spanish Association of Surgeons (AEC) in antibiotic prophylaxis in surgery
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Toro López, María Dolores del, Arias Díaz, Javier, Balibrea, José M., Benito, Natividad, Canut Blasco, Andrés, Muñoz Casares, Francisco Cristóbal, Badia, Josep M., Universidad de Sevilla. Departamento de Medicina, and Universidad de Sevilla. Departamento de Cirugía
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Infección de localización quirúrgica ,Prevención de la infección ,Surgical procedures ,Infection prevention ,Procedimientos quirúrgicos ,Antibiotic prophylaxis ,Profilaxis antibiótica ,Surgical site infection - Abstract
La profilaxis antibiótica en cirugía es una de las medidas más eficaces para la prevención de la infección de localización quirúrgica, aunque su uso es con frecuencia inadecuado, pudiendo incrementar el riesgo de infección, toxicidades y resistencias bacterianas. Debido al avance en las técnicas quirúrgicas y la emergencia de microorganismos multirresistentes las actuales pautas de profilaxis precisan ser revisadas. La Sociedad Española de Enfermedades Infecciosas (SEIMC), conjuntamente con la Asociación Española de Cirujanos (AEC) ha revisado y actualizado las recomendaciones de profilaxis antimicrobiana para adaptarlas a cada tipo de intervención quirúrgica y a la epidemiología actual. En este documento se recogen las recomendaciones de los antimicrobianos utilizados en profilaxis en los diferentes procedimientos, las dosis, la duración, la profilaxis en huéspedes especiales, y en situación epidemiológica de multirresistencia, de tal forma que permitan un manejo estandarizado, un uso racional, seguro y efectivo de los mismos en la cirugía electiva. Antibiotic prophylaxis in surgery is one of the most effective measures for preventing surgical site infection, although its use is frequently inadequate and may even increase the risk of infection, toxicities and antimicrobial resistance. As a result of advances in surgical techniques and the emergence of multidrug-resistant organisms, the current guidelines for prophylaxis need to be revised. The Sociedad Española de Enfermedades Infecciosas (Spanish Society of Infectious Diseases and Clinical Microbiology) (SEIMC) together with the Asociación Española de Cirujanos (Spanish Association of Surgeons) (AEC) have revised and updated the recommendations for antibiotic prophylaxis in surgery to adapt them to any type of surgical intervention and to current epidemiology. This document gathers together the recommendations on antimicrobial prophylaxis in the various procedures, with doses, duration, prophylaxis in special patient groups, and in epidemiological settings of multidrug resistance to facilitate standardized management and the safe, effective and rational use of antibiotics in elective surgery.
- Published
- 2021
7. Resumen ejecutivo del Documento de Consenso de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC) y de la Asociación Española de Cirujanos (AEC) en profilaxis antibiótica en cirugía
- Author
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Del Toro López, M Dolores, Arias Díaz, Javier, Balibrea, José M, Benito, Natividad, Canut Blasco, Andrés, Esteve, Erika, Horcajada, Juan Pablo, Ruiz Mesa, Juan Diego, Manuel Vázquez, Alba, Muñoz Casares, Cristóbal, Del Pozo, Jose Luis, Pujol, Miquel, Riera, Melchor, Jimeno, Jaime, Rubio Pérez, Inés, Ruiz-Tovar Polo, Jaime, Serrablo, Alejandro, Soriano, Alex, Badia, Josep M, and Grupo de Estudio de PA de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC) y Asociación Española de Cirujanos (AEC)
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Infección de localización quirúrgica ,Prevención de la infección ,Surgical procedures ,Infection prevention ,Procedimientos quirúrgicos ,Antibiotic prophylaxis ,Profilaxis antibiótica ,Surgical site infection - Abstract
Antibiotic prophylaxis in surgery is one of the most effective measures for preventing surgical site infection, although its use is frequently inadequate and may even increase the risk of infection, toxicities and antimicrobial resistance. As a result of advances in surgical techniques and the emergence of multidrug-resistant organisms, the current guidelines for prophylaxis need to be revised. The Sociedad Española de Enfermedades Infecciosas (Spanish Society of Infectious Diseases and Clinical Microbiology) (SEIMC) together with the Asociación Española de Cirujanos (Spanish Association of Surgeons) (AEC) have revised and updated the recommendations for antibiotic prophylaxis in surgery to adapt them to any type of surgical intervention and to current epidemiology. This document gathers together the recommendations on antimicrobial prophylaxis in the various procedures, with doses, duration, prophylaxis in special patient groups, and in epidemiological settings of multidrug resistance to facilitate standardized management and the safe, effective and rational use of antibiotics in elective surgery.
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- 2020
8. Implementation of the recommendations for prevention of surgical site infection in Spain: A survey to evaluate the gap between evidence-based recommendations and daily clinical practice in cardiovascular surgery
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Lopez-Menendez, Jose, Varela, Laura, Rodriguez-Roda, Jorge, Castano, Mario, Badia, Josep M., Balibrea, Jose M., and Centella, Tomasa
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Prevention ,Surveys and questionnaires ,Surgical site infection ,Cardiac surgical procedures - Abstract
Introduction: A panel constituted by experts from various surgical scientific societies have expressed their concern on the lack of knowledge of the implementation of evidence-based recommendations as regards surgical site infection (SSI) prevention in different surgical specialties in Spain. Methods: This expert panel designed an on-line questionnaire (SurveyMonkey (c)) consisting of 59 general questions for any surgical specialty, plus 5 more specific questions for Cardiac Surgery. Results: The questionnaire was completed by 82 cardiovascular surgeons from all over Spain, equally distributed into 1-10 years of experience (43%), 11-20 years (27%), and >20 years (30%). There was a high level of knowledge of specific protocols for patient surgical preparation (99%), patient safety in the operating room (87%), and contact isolation (96%). The results showed a lack of agreement between daily clinical practice and evidence-based recommendations in 4 strong recommendations of the World Health Organisation: screening/treatment of methicillin-resistant Staphylococcus aureus, hair removal, type/use of skin antiseptics, and duration of antibiotic prophylaxis. There were differences in another 4 conditional recommendations: preoperative nutritional status assessment, intraoperative glycaemic control, prophylactic use of negative pressure therapies, and antibiotic coated sutures. Conclusion: Several important improvement areas have been detected towards SSI prevention in Cardiovascular Surgery in Spain, as there are important differences between daily clinical practice and evidence-based recommendations for surgical site infection prevention.
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- 2020
9. A survey to identify the breach between evidence and practice in the prevention of surgical infection: Time to take action.
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Badia, Josep M., Casey, Anna L., Rubio-Pérez, Inés, Crosby, Cynthia, Arroyo-García, Nares, and Balibrea, José M.
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Background: The knowledge of the grade of implementation of preventative measures for surgical site infection (SSI) is crucial prior to planning dissemination strategies.Methods: Online survey among the members of the Spanish Association of Surgeons (AEC) to know the actual application of measures, and to compare them with new recommendations issued by international organizations.Results: Most of the 835 responding surgeons work in National Health Service Hospitals (91.3%). Surgeons of all super-specialties answered. 90.4% of responders recommend a preoperative shower, with normal soap or chlorhexidine. 60% recommend hair removal, preferably clipping, although 30% still recommend shaving. Povidone-iodine in aqueous solution or chlorhexidine in alcohol are used for skin preparation. Only 51.9% of surgeons allow solution to air drying before applying surgical drapes. In 83.2% of cases surgeons operate with a single pair of gloves. Perioperative normothermia and hyperoxia were used in 92% and 27.9% of cases, respectively. At the end of the procedure, peritoneal and wound lavage are used, in most cases with saline. Antimicrobial impregnated sutures are rarely used (85.7%) by surgeons, and 32% occasionally use negative pressure therapy on the closed wound.Conclusions: There is great variability in the level of awareness and application of the main measures of SSI prevention among Spanish surgeons. Several areas for improvement have been detected, as core prevention measures are not in common use, and discontinued practices are continued to be used. These practices should be addressed by the AEC by drafting specific recommendations for the prevention of SSI in Spanish hospitals. [ABSTRACT FROM AUTHOR]- Published
- 2018
- Full Text
- View/download PDF
10. An interventional nationwide surveillance program lowers postoperative infection rates in elective colorectal surgery. A cohort study (2008-2019).
- Author
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Arroyo-Garcia, Nares, Badia, Josep M., Vázquez, Ana, Pera, Miguel, Parés, David, Limón, Enric, Almendral, Alexander, Piriz, Marta, Díez, Cecilia, Fraccalvieri, Domenico, López-Contreras, Joaquín, Pujol, Miquel, Members of the VINCat Colorectal Surveillance Team, and VINCat Program
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ELECTIVE surgery ,DIGESTIVE organ surgery ,SURGICAL site infections ,MEDICAL specialties & specialists ,LONGITUDINAL method - Abstract
Background: Colorectal surgery is associated with the highest rate of surgical site infection (SSI). This study analyses the effectiveness of an interventional surveillance program on SSI rates after elective colorectal surgery.Material and Methods: Cohort study showing temporal trends of SSI rates and Standardized Infection Ratio (SIR) in elective colorectal surgery over a 12-year period. Prospectively collected data of a national SSI surveillance program was analysed and the effect of specific interventions was evaluated. Patient and procedure characteristics, as well as SIR and SSI rates were stratified by risk categories and type of SSI analysed using stepwise multivariate logistic regression models.Results: In a cohort of 42,330 operations, overall cumulative SSI incidence was 16.31%, and organ-space SSI (O/S-SSI) was 8.59%. There was a 61.63% relative decrease in SSI rates (rho = -0.95804). The intervention which achieved the greatest SSI reduction was a bundle of 6 measures. SSI in pre-bundle period was 19.73% vs. 11.10% in post-bundle period (OR 1.969; IC 95% 1.860-2.085; p < 0.0001). O/S-SSI were 9.08% vs. 6.06%, respectively (OR 1.547; IC 95% 1.433-1.670; p < 0.0001). Median length of stay was 7 days, with a significant decrease over the studied period (rho = -0.98414). Mortality of the series was 1.08%, ranging from 0.35% to 2.0%, but a highly significant decrease was observed (rho = -0.67133).Conclusions: Detailed analysis of risk factors and postoperative infection in colorectal surgery allows strategies for reducing SSI incidence to be designed. An interventional surveillance program has been effective in decreasing SIR and SSI rates. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
11. Oral Antibiotic Prophylaxis Lowers Surgical Site Infection in Elective Colorectal Surgery: Results of a Pragmatic Cohort Study in Catalonia.
- Author
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Badia, Josep M., Flores-Yelamos, Miriam, Vázquez, Ana, Arroyo-García, Nares, Puig-Asensio, Mireia, Parés, David, Pera, Miguel, López-Contreras, Joaquín, Limón, Enric, and Pujol, Miquel
- Subjects
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SURGICAL site infections , *ELECTIVE surgery , *ANTIBIOTIC prophylaxis , *PROCTOLOGY , *COHORT analysis , *UNIVARIATE analysis - Abstract
Background: The role of oral antibiotic prophylaxis (OAP) and mechanical bowel preparation (MBP) in the prevention of surgical site infection (SSI) after colorectal surgery is still controversial. The aim of this study was to analyze the effect of a bundle including both measures in a National Infection Surveillance Network in Catalonia. Methods: Pragmatic cohort study to assess the effect of OAP and MBP in reducing SSI rate in 65 hospitals, comparing baseline phase (BP: 2007–2015) with implementation phase (IP: 2016–2019). To compare the results, a logistic regression model was established. Results: Out of 34,421 colorectal operations, 5180 had SSIs (15.05%). Overall SSI rate decreased from 18.81% to 11.10% in BP and IP, respectively (OR 0.539, CI95 0.507–0.573, p < 0.0001). Information about bundle implementation was complete in 61.7% of cases. In a univariate analysis, OAP and MBP were independent factors in decreasing overall SSI, with OR 0.555, CI95 0.483–0.638, and OR 0.686, CI95 0.589–0.798, respectively; and similarly, organ/space SSI (O/S-SSI) (OR 0.592, CI95 0.494–0.710, and OR 0.771, CI95 0.630–0.944, respectively). However, only OAP retained its protective effect at both levels at multivariate analyses. Conclusions: oral antibiotic prophylaxis decreased the rates of SSI and O/S-SSI in a large series of elective colorectal surgery. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
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