1. Diffraction-Enhanced Computed Tomographic Imaging of Growing Piglet Joints by Using a Synchrotron Light Source.
- Author
-
Rhoades GW, Belev GS, Chapman LD, Wiebe SP, Cooper DM, Wong AT, and Rosenberg AM
- Subjects
- Age Factors, Animals, Animals, Newborn, Cartilage, Articular diagnostic imaging, Cartilage, Articular growth & development, Male, Predictive Value of Tests, Radiographic Image Interpretation, Computer-Assisted, Swine, Arthrography instrumentation, Arthrography methods, Joints growth & development, Synchrotrons, Tomography, X-Ray Computed
- Abstract
The objective of this project was to develop and test a new technology for imaging growing joints by means of diffraction-enhanced imaging (DEI) combined with CT and using a synchrotron radiation source. DEI-CT images of an explanted 4-wk-old piglet stifle joint were acquired by using a 40-keV beam. The series of scanned slices was later 'stitched' together, forming a 3D dataset. High-resolution DEI-CT images demonstrated fine detail within all joint structures and tissues. Striking detail of vasculature traversing between bone and cartilage, a characteristic of growing but not mature joints, was demonstrated. This report documents for the first time that DEI combined with CT and a synchrotron radiation source can generate more detailed images of intact, growing joints than can currently available conventional imaging modalities.
- Published
- 2015