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Collet-Sicard syndrome (CSS) is the unilateral palsy of the cranial nerves (CN) IX, X, XI, and XII. To our knowledge, no review describes the characteristics of patients diagnosed with CSS. Therefore, this review aims to collect and describe all cases in the literature labeled as CSS. We performed a scoping review of the literature and conducted a database search in Embase and PubMed. We included articles and abstracts with case reports or case series of patients with CSS diagnosis. We classified the cases into two groups: "CSS", referring to patients presenting exclusively with IX-XII nerve involvement, and "CSS-plus", which corresponds to cases with CSS and other neurological impairments. We included 135 patients from 126 articles, of which 84 (67.7%) were male. The most common clinical manifestations reported were dysphagia and dysphonia. The most common etiology was tumoral in 53 cases (39.6%) and vascular in 37 cases (27.6%). The majority of patients showed partial or total improvement, with just over half receiving conservative treatment. The most frequent anatomic space was the jugular foramen (44.4%) and the parapharyngeal retrostyloid space (28.9%). Approximately 21% of the patients had other CN impairments, with the seventh and eighth CN most frequently compromised. We conclude that although there is a need for greater rigor in CSS reporting, the syndrome has a clear utility in identifying the localization of jugular foramen and parapharyngeal retrostyloid space pathology. [ABSTRACT FROM AUTHOR]

This document is a reply to a letter to the editor regarding a scoping review on Collet-Sicard Syndrome (CSS). The authors of the original article thank Dr. Nathan Beucler for his interest and explain their research methodology. They conducted a systematic search of articles that mentioned CSS in the title and focused on patients with involvement of cranial nerves IX-XII. They did not analyze outcomes due to the variability of etiologies and lack of homogeneity between studies. The authors acknowledge Dr. Beucler's insights and suggest that their research, along with his suggestions, could lead to further investigation on CSS treatment options and functional outcomes. [Extracted from the article]