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Your search keyword '"Gascoigne, Nicholas R. J."' showing total 20 results

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1. Themis is indispensable for IL-2 and IL-15 signaling in T cells.

2. Non-Stimulatory pMHC Enhance CD8 T Cell Effector Functions by Recruiting Coreceptor-Bound Lck.

3. Expansion of an Unusual Virtual Memory CD8+ Subpopulation Bearing Vα3.2 TCR in Themis-Deficient Mice.

4. Lck bound to coreceptor is less active than free Lck.

5. A Dual Inhibitor of Cdc7/Cdk9 Potently Suppresses T Cell Activation.

6. Themis-associated phosphatase activity controls signaling in T cell development.

7. Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand Recognition.

8. Allelic Exclusion of TCR α-Chains upon Severe Restriction of Vα Repertoire.

9. Protein kinase C-η controls CTLA-4-mediated regulatory T cell function.

10. Themis sets the signal threshold for positive and negative selection in T-cell development.

11. The role of protein kinase Cη in T cell biology.

12. Themis controls thymocyte selection through regulation of T cell antigen receptor–mediated signaling.

13. Do T cells need endogenous peptides for activation?

14. Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling.

15. TCR affinity and negative regulation limit autoimmunity.

16. Surprisingly minor influence of TRAV11 (Vα14) polymorphism on NK T-receptor mCD1/α-galactosylceramide binding kinetics.

17. Targeting CAR to the Peptide-MHC Complex Reveals Distinct Signaling Compared to That of TCR in a Jurkat T Cell Model.

18. Taming the Sentinels: Microbiome-Derived Metabolites and Polarization of T Cells.

19. Immunology: Tolerance lies in the timing.

20. GRB2-Mediated Recruitment of THEMIS to LAT Is Essential for Thymocyte Development.

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