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A total of 32 patients with aggravated chronic pyo-obstructive bronchitis were studied. Various immunological disorders and impaired non-specific responsiveness were detected in this group of patients. With this, abnormal T cellular immunity (reduced T cell counts at the expense of T helpers and their reaction to PGA) was the leading T cell immunity disorder. In the presence of the available immunity abnormalities, responses to inflammation (B-systems) and non-specific responsiveness were less pronounced. During treatment, the patients without substantial immunity disorders had normalized parameters of immunity and non-specific responsiveness, whereas the patients displayed this. The clinical efficacy of treatment was higher in patients without significant abnormalities in immunity and non-specific responsiveness.

Forty-three patients with traumatic osteomyelitis developing after combined maxillofacial and craniocerebral injuries and thirty normal subjects were examined. Immunologic findings permit distinguishing two groups of patients: those with marked disorders of the T cellular immunity (reduced T helper and Tx counts, interleukin-2 synthesis, and Tx/T suppressor coefficient) and without such shifts. The therapy of patients without manifest immunity shifts was generally effective whereas in those with marked immunity disorders the therapy efficacy was inadequate and the immunity disorders persisted.