Search

Environmental exposures during pregnancy have been associated with adverse obstetric outcomes. However, limited and inconsistent evidence exists regarding the association between air temperature exposure and the risk of preeclampsia (PE). This study aimed to evaluate the correlation between ambient temperature exposure during pregnancy and PE risk, as well as identify the specific time window of temperature exposure that increases PE risk. A population-based cohort study was conducted from January 2012 to April 2022 in Guangzhou, China. Pregnant women were recruited in early pregnancy and followed until delivery. A total of 3,314 PE patients and 114,201 normal pregnancies were included. Ambient temperature exposures at different gestational weeks were recorded for each participant. Logistic regression models were used to evaluate the correlation between ambient temperature exposure and PE risk. Stratified analyses were conducted based on maternal age and pre-pregnancy BMI. Distributed lag models were employed to identify the time window of temperature exposure related to PE. Exposure to extreme high temperature (aOR = 1.24, 95 % CI 1.12-1.38) and moderate high temperature (aOR = 1.22, 95 % CI 1.10-1.35) during early pregnancy was associated with an increased risk of PE. Furthermore, women with higher pre-pregnancy BMI had a higher risk of developing PE when exposed to high temperature during early pregnancy compared to normal-weight women. The time window of temperature exposure related to PE was identified as pregnancy weeks 1 to 8. This study provides evidence for the association of high temperature exposure during early pregnancy with the risk of PE, as well as identifies the specific time window of temperature exposure related to PE. These findings have implications for developing potential strategies to protect pregnant women, particularly those with higher pre-pregnancy BMI, from the adverse effects of extreme temperatures during early pregnancy., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)

Three-dimensional numerical simulations are carried out to investigate the temperature field in the contact zone due to the thermal loading of the workpiece in surface grinding. This technique considers that the thermophysical properties of the workpiece material are non-linear according to temperature, the contact zone between the wheel and the workpiece is assumed as an arc surface, and the heat flux entering the workpiece is assumed as proportional to the local undeformed chip thickness. A good agreement is found between the simulated results and the experimental observations. The high grinding temperature leads to the thermal expansion of the workpiece material, which causes the thickness of the actual material removal layer to be larger than the cutting depth. The grinding temperature at the central portion is higher than that on the side of the workpiece during the wet grinding, thus the material removal layer in the central zone is thicker than that on the side zone, and the workpiece surface is concave across the grinding width. [ABSTRACT FROM AUTHOR]