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Your search keyword '"Virilism prevention & control"' showing total 12 results
Start Over Descriptor "Virilism prevention & control" Topic therapeutic human experimentation
12 results on '"Virilism prevention & control"'

1. Vindication of prenatal diagnosis and treatment of congenital adrenal hyperplasia with low-dose dexamethasone.

Author

New MI

Subjects
Adrenal Hyperplasia, Congenital complications, Drug Administration Schedule, Drug Approval, Ethics Committees, Research, Female, Glucocorticoids administration & dosage, Humans, Off-Label Use, Pregnancy, Rare Diseases diagnosis, Rare Diseases drug therapy, United States, United States Food and Drug Administration, Virilism etiology, Adrenal Hyperplasia, Congenital diagnosis, Adrenal Hyperplasia, Congenital drug therapy, Dexamethasone administration & dosage, Prenatal Diagnosis, Therapeutic Human Experimentation ethics, Virilism prevention & control
Published
2010
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2. The view from the inside: more confusion (and coziness) than consent.

Author

Green J

Subjects
Clinical Trials as Topic, Dexamethasone adverse effects, Disorders of Sex Development etiology, Ethics Committees, Research, Female, Glucocorticoids administration & dosage, Glucocorticoids adverse effects, Humans, Mass Screening, Prenatal Diagnosis, Societies, United States, United States Food and Drug Administration, Virilism prevention & control, Adrenal Hyperplasia, Congenital complications, Adrenal Hyperplasia, Congenital diagnosis, Adrenal Hyperplasia, Congenital drug therapy, Dexamethasone administration & dosage, Disorders of Sex Development prevention & control, Fetal Diseases diagnosis, Fetal Diseases drug therapy, Informed Consent ethics, Patient Advocacy, Therapeutic Human Experimentation ethics
Published
2010
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3. On cultural sanctions for shaping our children's genitalia.

Author

Lantos J

Subjects
Adrenal Hyperplasia, Congenital complications, Dexamethasone adverse effects, Disorders of Sex Development etiology, Ethics Committees, Research, Female, Fetal Diseases diagnosis, Glucocorticoids adverse effects, Humans, Prenatal Diagnosis, Randomized Controlled Trials as Topic ethics, United States, United States Food and Drug Administration, Virilism prevention & control, Adrenal Hyperplasia, Congenital diagnosis, Cultural Characteristics, Dexamethasone administration & dosage, Disorders of Sex Development prevention & control, Fetal Diseases drug therapy, Genitalia, Female abnormalities, Glucocorticoids administration & dosage, Therapeutic Human Experimentation ethics
Published
2010
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4. Quo OHRP?: faithful arbiter or pro wrestling ref?

Author

Dolan T

Subjects
Adrenal Hyperplasia, Congenital complications, Adrenal Hyperplasia, Congenital diagnosis, Adrenal Hyperplasia, Congenital drug therapy, Bioethical Issues, Disorders of Sex Development etiology, Ethics Committees, Research, Female, Humans, United States, Virilism prevention & control, Dexamethasone administration & dosage, Disorders of Sex Development prevention & control, Glucocorticoids administration & dosage, Terminology as Topic, Therapeutic Human Experimentation ethics, Whistleblowing
Published
2010
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5. Description and defense of prenatal diagnosis and treatment with low-dose dexamethasone for congenital adrenal hyperplasia.

Author

New M

Subjects
Adrenal Hyperplasia, Congenital enzymology, Algorithms, Disorders of Sex Development etiology, Drug Administration Schedule, Ethics Committees, Research, Female, Fetal Diseases enzymology, Genitalia, Female surgery, Glucocorticoids administration & dosage, Humans, Plastic Surgery Procedures, Referral and Consultation, Steroid 21-Hydroxylase metabolism, United States, Virilism prevention & control, Adrenal Hyperplasia, Congenital complications, Adrenal Hyperplasia, Congenital diagnosis, Dexamethasone administration & dosage, Disorders of Sex Development prevention & control, Fetal Diseases diagnosis, Prenatal Diagnosis, Therapeutic Human Experimentation ethics
Published
2010
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6. Why history matters: fetal dex and intersex.

Author

Reis E and Kessler S

Subjects
Adrenal Hyperplasia, Congenital complications, Adrenal Hyperplasia, Congenital diagnosis, Adrenal Hyperplasia, Congenital history, Disorders of Sex Development etiology, Female, Fetal Diseases diagnosis, Fetal Diseases history, Genitalia, Female abnormalities, History, 19th Century, History, 20th Century, History, 21st Century, Homosexuality, Humans, Plastic Surgery Procedures history, Virilism prevention & control, Adrenal Hyperplasia, Congenital drug therapy, Dexamethasone administration & dosage, Disorders of Sex Development prevention & control, Fetal Diseases drug therapy, Genitalia, Female surgery, Glucocorticoids administration & dosage, Therapeutic Human Experimentation ethics
Published
2010
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7. Speaking of accuracy.

Author

Frader J

Subjects
Adrenal Hyperplasia, Congenital complications, Dexamethasone adverse effects, Disorders of Sex Development etiology, Drug Administration Schedule, Female, Fetal Diseases diagnosis, Glucocorticoids administration & dosage, Glucocorticoids adverse effects, Humans, Informed Consent ethics, Informed Consent standards, Off-Label Use ethics, Prenatal Diagnosis, Virilism prevention & control, Adrenal Hyperplasia, Congenital diagnosis, Adrenal Hyperplasia, Congenital drug therapy, Dexamethasone administration & dosage, Disorders of Sex Development prevention & control, Fetal Diseases drug therapy, Therapeutic Human Experimentation ethics
Published
2010
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8. An attempt to shut down discourse about a controversial practice will not benefit patients, human subjects, the bioethics community, or the research community.

Author

Tamar-Mattis A

Subjects
Adrenal Hyperplasia, Congenital complications, Adrenal Hyperplasia, Congenital drug therapy, Disorders of Sex Development etiology, Ethics Committees, Research, Female, Fetal Diseases diagnosis, Glucocorticoids administration & dosage, Humans, Informed Consent ethics, Virilism prevention & control, Adrenal Hyperplasia, Congenital diagnosis, Dexamethasone administration & dosage, Disorders of Sex Development prevention & control, Fetal Diseases drug therapy, Therapeutic Human Experimentation ethics
Published
2010
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9. A case study in unethical transgressive bioethics: "Letter of concern from bioethicists" about the prenatal administration of dexamethasone.

Author

McCullough LB, Chervenak FA, Brent RL, and Hippen B

Subjects
Adrenal Hyperplasia, Congenital complications, Adrenal Hyperplasia, Congenital enzymology, Clinical Trials as Topic, Disorders of Sex Development etiology, Drug Administration Schedule, Ethics Committees, Research, Female, Fetal Diseases diagnosis, Fetal Diseases enzymology, Genitalia, Female surgery, Glucocorticoids administration & dosage, Humans, Informed Consent ethics, Male, Pregnancy, Plastic Surgery Procedures, Referral and Consultation, Steroid 21-Hydroxylase metabolism, United States, United States Food and Drug Administration, Virilism prevention & control, Adrenal Hyperplasia, Congenital diagnosis, Adrenal Hyperplasia, Congenital drug therapy, Correspondence as Topic, Dexamethasone administration & dosage, Disorders of Sex Development prevention & control, Ethicists standards, Fetal Diseases drug therapy, Genitalia, Female abnormalities, Off-Label Use ethics, Prenatal Diagnosis, Therapeutic Human Experimentation ethics
Abstract

On February 3, 2010, a "Letter of Concern from Bioethicists," organized by fetaldex.org, was sent to report suspected violations of the ethics of human subjects research in the off-label use of dexamethasone during pregnancy by Dr. Maria New. Copies of this letter were submitted to the FDA Office of Pediatric Therapeutics, the Department of Health and Human Services (DHHS) Office for Human Research Protections, and three universities where Dr. New has held or holds appointments. We provide a critical appraisal of the Letter of Concern and show that it makes false claims, misrepresents scientific publications and websites, fails to meet standards of evidence-based reasoning, makes undocumented claims, treats as settled matters what are, instead, ongoing controversies, offers "mere opinion" as a substitute for argument, and makes contradictory claims. The Letter of Concern is a case study in unethical transgressive bioethics. We call on fetaldex.org to withdraw the letter and for co-signatories to withdraw their approval of it.

Published
2010
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10. Attracting attention: right or wrong.

Author

Robichaud A

Subjects
Adrenal Hyperplasia, Congenital complications, Adrenal Hyperplasia, Congenital drug therapy, Clinical Trials as Topic ethics, Disorders of Sex Development etiology, Ethics Committees, Research, Female, Fetal Diseases diagnosis, Fetal Diseases drug therapy, Glucocorticoids administration & dosage, Humans, Informed Consent ethics, Off-Label Use ethics, United States, Virilism prevention & control, Adrenal Hyperplasia, Congenital diagnosis, Correspondence as Topic, Dexamethasone administration & dosage, Disorders of Sex Development prevention & control, Therapeutic Human Experimentation ethics
Published
2010
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11. Why I signed, and why I would do it again.

Author

Kraft RE Jr

Subjects
Bioethics education, Disorders of Sex Development etiology, Ethical Analysis, Ethics Committees, Research, Female, Glucocorticoids administration & dosage, Humans, Off-Label Use ethics, Virilism prevention & control, Adrenal Hyperplasia, Congenital complications, Adrenal Hyperplasia, Congenital diagnosis, Adrenal Hyperplasia, Congenital drug therapy, Correspondence as Topic, Dexamethasone administration & dosage, Disorders of Sex Development prevention & control, Fetal Diseases diagnosis, Fetal Diseases drug therapy, Therapeutic Human Experimentation ethics
Published
2010
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12. Still concerned.

Author

Dreger A, Feder EK, and Lindemann H

Subjects
Adrenal Hyperplasia, Congenital complications, Clinical Trials as Topic, Disorders of Sex Development etiology, Female, Humans, Informed Consent ethics, Male, Pregnancy, Prenatal Diagnosis, Virilism prevention & control, Adrenal Hyperplasia, Congenital diagnosis, Dexamethasone administration & dosage, Disorders of Sex Development prevention & control, Glucocorticoids administration & dosage, Off-Label Use ethics, Therapeutic Human Experimentation ethics
Published
2010
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