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The article discusses the British Society for Haematology's (BSH) guidelines on the management of thrombotic and haemostatic issues in paediatric malignancy. Topics discussed include the methodology for the creation of the guidelines, venous thromboembolism (VTE) and bleeding as serious complications of cancer and its treatment, assessing and reducing the risk of VTE, treatment of various types of VTE, management of thrombocytopenia and coagulopathy and therapy for menstrual suppression.

Thrombosis in children is becoming more prevalent due to increased awareness of these issues in the pediatric population and advances in medicine. Management of affected children are challenging due to differences in their hemostatic system compared with adults. Prospective, controlled trials for management/treatment of children with thrombosis are lacking. Many of the available guidelines for treatment of thrombosis in children are extrapolated from adult data and do not account for the uniqueness of the pediatric hemostatic system, although more research and data are becoming available. This review will focus on children over 1 year of age, including adolescents, looking at the etiology of thrombosis, diagnosis, management options, and any associated complications in this pediatric population. [ABSTRACT FROM AUTHOR]