1. Circadian thyrotropin variations are preserved in normal pregnant women.
- Author
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Roti E, Bartalena L, Minelli R, Salvi M, Gardini E, Pistolesi A, Martino E, and Braverman LE
- Subjects
- Adult, Female, Humans, Pregnancy, Thyroxine blood, Triiodothyronine blood, Circadian Rhythm physiology, Pregnancy Trimester, Second blood, Pregnancy Trimester, Third blood, Thyrotropin blood
- Abstract
Serum thyrotropin (TSH) concentration circadian rhythm is abolished in many endocrine and non-endocrine diseases. In the present study we have measured serum TSH concentration over 24 h every 2 h in second and third trimester pregnant women. During the 24-h period, serum free thyroxine and free triiodothyronine concentrations did not change significantly. In contrast, serum TSH concentrations demonstrated significant circadian variations both in the second and third trimester pregnant women (p < 0.02 and p < 0.005, respectively). In summary, second and third trimester pregnancy is associated with a normal circadian TSH rhythm.
- Published
- 1995
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