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Purpose: In patients with moderate-to-severe bilateral medial knee osteoarthritis, it is difficult to determine the necessity of the subsequent contralateral total knee arthroplasty (TKA) after performing the first procedure. This study aimed to compare patient characteristics and clinical outcomes between patients who underwent staged bilateral TKA (group B) and those who underwent unilateral TKA (group U) to identify predictors of contralateral TKA requirement. Methods: Among 153 patients with bilateral medial knee osteoarthritis of Kellgren-Lawrence grade 3 or 4, 43 and 110 patients underwent unilateral and bilateral TKA, respectively. Clinical evaluations using the patient-reported outcome measure (the Japanese Knee Osteoarthritis Measure [JKOM]), the Knee Society Score (KSS), and the timed “Up and Go” test (TUG) were performed preoperatively, at 12 months, and once every year up to 5 years after the unilateral and the contralateral TKA in groups U and B, respectively. Receiver Operating Characteristic (ROC) analysis was used to determine the cut-off value for preoperative JKOM score that indicates the contralateral TKA. Results: There were no significant differences in patient characteristics between groups B and U. The preoperative JKOM scores were significantly worse in group B. Postoperative improvements in JKOM, KSS, and TUG were statistically significant in both groups; however, there were no significant differences in post-procedure scores between the two groups. ROC analysis showed that the optimal cut-off value of the preoperative JKOM score was 41.5 points. Conclusion: A preoperative JKOM score of ≥41.5 is a possible predictor of the contralateral TKA in patients with moderate-to-severe bilateral medial knee osteoarthritis.

Background: There are many risk factors for arthrofibrosis and manipulation under anesthesia (MUA) following total knee arthroplasty (TKA). However, no study has elucidated whether a history of MUA increases the risk of contralateral MUA in patients undergoing staged bilateral TKA.Methods: A retrospective review of an institutional database of TKAs was performed. All patients aged ≥18 years who underwent primary staged bilateral TKAs were screened for inclusion. Staged bilateral TKAs were viewed as 2 distinct events based on the temporal order in which they occurred: TKA#1 (occurred first) and TKA#2 (occurred second). Following TKA#1, patients were split into 2 groups: those who underwent MUA (Group MANIP) and those who did not (Group NO MANIP). The subsequent risk of undergoing MUA following TKA#2 was then assessed and compared between the 2 groups. Chi-squared tests were used for comparison.Results: A total of 5,330 patients who underwent primary uncomplicated staged bilateral TKAs (10,660 knees) during the study period were identified. Overall, 2.1% of patients underwent MUA following TKA#1 and 1.9% of patients underwent MUA following TKA#2. In the MANIP group, 21.4% of patients underwent MUA following TKA#2, while only 1.5% underwent MUA in the NO MANIP group. This 14.3-fold increase in the risk of MUA in the MANIP group following TKA#2 was statistically significant (21.4% vs 1.5%, absolute risk reduction = 19.9%, relative risk reduction = 93.0%, P < .0001).Conclusion: Patients who undergo MUA during the first TKA of a staged bilateral TKA are 14.3 times more likely to undergo a subsequent MUA than those who did not undergo MUA following their first TKA. [ABSTRACT FROM AUTHOR]

Background: The objective of the study was to analyze if the length of interval time between stages influenced functional and quality of life outcomes in patients with staged bilateral primary total knee arthroplasty (TKA).Methods: This is a retrospective comparative study between 93 patients with an interval between stages of 6-8 months (6-month group), 112 of 12-14 months (1-year group), and 108 of 24-26 months (2-year group). Outcome variables were Knee Society scores, Western Ontario and McMaster Universities, Short Form, and patient satisfaction.Results: Overall, the mean follow-up for the first TKA was 8.2 (range, 7-10) years, and for the second TKA, 6.7 (range, 5-10) years. At last follow-up, functional and patient-related outcomes were similar for both knees, regardless of the interval. However, mental score and patient satisfaction were significantly better for the second than for the first TKA in the 2-year group. Age did not correlate significantly with the functional scores but was significantly correlated with the mental score.Conclusion: The performing staged bilateral TKA with a wide interval between surgeries provided equivalent functional outcomes and quality of life for both knees. Postoperative outcomes were not affected by the length of the time interval between procedures or age. Our results can help the surgeon to inform the patients reliably about what they can expect in the delay of a second knee replaced. Thus, patients could make an informed decision. [ABSTRACT FROM AUTHOR]