1. Triterpenoids from the bark of Entandrophragma angolense .
- Author
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Trinh BTD, Bui DN, Nguyen LTT, Nguyen HT, Nguyen CN, Nguyen LD, Huynh TNM, Cao TTC, and Nguyen LT
- Subjects
- Humans, Molecular Structure, Plant Bark chemistry, Magnetic Resonance Spectroscopy, Hep G2 Cells, Triterpenes chemistry, Meliaceae chemistry
- Abstract
Two new triterpenoids, entanolide ( 1 ) and methyl 3,4-secotirucalla-23-oxo-4(28),7,24-trien-21-al-3-oate ( 2 ), together with nine known compounds ( 3-11 ), were isolated from the bark of Entandrophragma angolense . Their structures were elucidated based on spectroscopic analyses, mainly 1 D and 2 D NMR spectral data. Compounds 1 - 6 and 8 were evaluated for their cytotoxicity against HepG2 cells, and compounds 2-5 exhibited weak activities.
- Published
- 2023
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