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Start Over Author "Chiancone F" Topic tryptophan
14 results on '"Chiancone F"'

1. [Changes in opposite directions of tryptophanpyrrolase and 3-OH-anthranilic oxidase after a loading dose of tryptophan].

Author

Chiancone FM

Subjects
3-Hydroxyanthranilic Acid, Animals, Kidney drug effects, Kidney enzymology, Liver drug effects, Liver enzymology, Prednisolone administration & dosage, Prednisolone pharmacology, Rats, Tryptophan administration & dosage, Oxygenases metabolism, Tryptophan pharmacology, Tryptophan Oxygenase metabolism
Abstract

A loading dose of tryptophan induces a marked increase of tryptophan-pyrrolase (substrate induction) and a decrease of 3-OH-anthranilic-oxidase values in rat liver; in the kidneys of the same experimental animals the 3-OH-anthranilic-oxydase is instead unchanged. In other experimental conditions (surrenectomized or pyridoxine depleted rats, with or without tryptophan loading; with prednisolone loading) a more or less important substrate induction is always reported, whereas no variation occurs in the values of 3-OH-anthranilic-oxydase. These data are not sufficient to state whether there is a connection between the opposite responses of the two enzymatic activities obtained after tryptophan loading in rat liver homogenate. On the other hand, it should be kept in mind that they do not represent the overall effect induced by the aminoacid loading, but refer only to one moment of the action exerted by the loading itself. In order to acquire a thorough knowledge of the observations made so far and to formulate some assumptions which may be helpful for the interpretation of the relevant mechanisms, it is necessary to investigate the kinetics of both enzymes, and to study their regulatory mechanisms in particular after tryptophan loading.

Published
1978

3. [Urinary xanthurenic acid levels].

Author

Chiancone FM

Subjects
Age Factors, Aged, Alcoholism urine, Arthritis, Rheumatoid urine, Child, Contraceptives, Oral adverse effects, Diabetes Mellitus urine, Epilepsy urine, Female, Humans, Isoniazid adverse effects, Penicillamine adverse effects, Pregnancy, Tryptophan metabolism, Xanthurenates urine
Published
1978

8. [Tryptophan metabolism in screening metabolic diseases of the newborn].

Author

Chiancone FM, Mainardi L, and Tenconi LT

Subjects
Amino Acid Metabolism, Inborn Errors diagnosis, Amino Acid Metabolism, Inborn Errors metabolism, Evaluation Studies as Topic, Female, Humans, Infant, Newborn, Infant, Premature, Liver enzymology, Mass Screening, Metabolism, Inborn Errors metabolism, Methods, Niacinamide urine, Pregnancy, Tryptophan urine, Tryptophan Oxygenase metabolism, Infant, Newborn, Diseases metabolism, Metabolism, Inborn Errors diagnosis, Tryptophan metabolism
Published
1973

10. [Functional exploration at various levels of the tryptophan--nicotinic acid metabolic line].

Author

Chiancone FM

Subjects
Diabetes Mellitus metabolism, Down Syndrome metabolism, Female, Humans, Hydroxyindoleacetic Acid metabolism, Hydroxylation, Kynurenine metabolism, Male, Oxidation-Reduction, Pregnancy, Serotonin metabolism, Vitamin B 6 Deficiency metabolism, ortho-Aminobenzoates metabolism, Nicotinic Acids metabolism, Tryptophan metabolism
Published
1972

11. [HEPATIC TRYPTOPHAN-PYRROLASE IN EXPERIMENTAL PHYSIOLOGY AND PATHOLOGY].

Author

CHIANCONE FM

Subjects
Guinea Pigs, Rabbits, Rats, Biotin, Dietary Fats, Endocrine Glands, Hormones, Liver, Liver Diseases, Metabolism, Neoplasms, Neoplasms, Experimental, Niacin, Pantothenic Acid, Peroxidases, Pharmacology, Physiology, Thiamine, Tryptophan, Tryptophan Oxygenase, Vitamin B 6 Deficiency
Published
1963

13. [Tryptophan-nicotinic acid metabolism in psychiatric diseases].

Author

Chiancone FM

Subjects
Female, Humans, Male, Adult, Child, Child, Preschool, Chromatography, Down Syndrome drug therapy, Down Syndrome metabolism, Intellectual Disability drug therapy, Intellectual Disability metabolism, Nicotinic Acids metabolism, Nicotinic Acids therapeutic use, Nicotinic Acids urine, Schizophrenia drug therapy, Schizophrenia metabolism, Sex Factors, Tryptophan metabolism, Tryptophan therapeutic use, Tryptophan urine
Published
1968

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