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The reaction of N‐(4‐methyl‐2‐pyridinyl)‐P,P‐diphenylphosphinous amide ligand 4‐Me‐C5H3N‐2‐NH(PPh2) (1) with M(CO)6 (M=Cr, Mo, W) in refluxing toluene afforded a mononuclear group VIB metal tetracarbonyls [M(CO)4{1‐κ2P,N}] (M=Cr(2), Mo(3), W(4)). Complexes 2–4 were characterized by multinuclear NMR (1H, 13C and 31P NMR) and IR spectroscopy, and their structures were also determined by single crystal X‐ray diffraction. 2 and 4 represent the first examples of structurally characterized complexes of such ligands with group 6B metal carbonyls. [ABSTRACT FROM AUTHOR]

Reactions of monooxidized thioyl and selenoyl bis(phosphanyl)amine ligands C10H7-1-N(P( E)Ph2)(PPh2) [ E = S ( 1), Se ( 2)] with Mo(CO)4(pip)2 and W(CO)4(cod) afforded the complexes [ M(CO)4{ 1-κ2 P,S}] [ M = Mo ( 3), W ( 4)] and [ M(CO)4{ 2-κ2 P,Se}] [ M = Mo ( 5), W ( 6)]. Complexes 3- 6 were characterized by multinuclear NMR (1H, 13C, 31P, and 77Se NMR) and IR spectroscopy. Crystal-structure determinations were carried out on 3, 5, and 6, which represent the first examples of structurally characterized complexes of such ligands with group-6 metal carbonyls. [ABSTRACT FROM AUTHOR]

N,N-dimethyl- o -toluidine was treated with n -butyllithium-tmeda in diethylether/hexane solution to give (2-(dimethylamino)benzyl)lithium which reacts with chlorodiphenylphosphine to form the corresponding hemilabile N,P -ligand 2-PPh 2 CH 2 -1-NMe 2 C 6 H 4 (1). Oxidation of 1 with elemental sulfur or gray selenium gave the corresponding sulfide and selenide 2-(E)PPh 2 CH 2 -1-NMe 2 C 6 H 4 (E = S (2), Se (3)), respectively. The reaction of 1 with M(CO) 6 (M = Mo, W) afforded cis -[Mo(CO) 4 {2-PPh 2 CH 2 -1-NMe 2 C 6 H 4 } 2 (4) and trans- [W(CO) 4 {2-PPh 2 CH 2 -1-NMe 2 C 6 H 4 } 2 (5), respectively. The treatment of 1 with copper(I) iodide in 1:1 mol ratio produced [CuI{2-PPh 2 CH 2 -1-NMe 2 C 6 H 4 }] 2 (6). The complexes 4 – 6 have been screened for antibacterial activity and the results were compared with the activity of the free ligand 1 against four bacterial strains. Complexes 4 and 6 had the highest antibacterial activity and can be considered as promising antimicrobial agents. Compounds 1 – 6 were characterized by multinuclear NMR spectroscopy (1H, 13C, 31P, 77Se NMR), IR and elemental analysis. Crystal structure determinations of 1 , 2 , 4 , and 6 were carried out. Image 1 • Oxidation of 2-PPh 2 CH 2 -1-NMe 2 C 6 H 4 (1) with sulfur or selenium gave 2-(E)PPh 2 CH 2 -1-NMe 2 C 6 H 4 (E = S (2), Se (3)). • Cis -[Mo(CO) 4 {2-PPh 2 CH 2 -1-NMe 2 C 6 H 4 } 2 (4) and trans- [W(CO) 4 {2-PPh 2 CH 2 -1-NMe 2 C 6 H 4 } 2 (5) were synthesized. • The treatment of 1 with copper(I) iodide produced [CuI{2-PPh 2 CH 2 -1-NMe 2 C 6 H 4 }] 2 (6). • The complexes 4 – 6 have been screened for antibacterial activity. [ABSTRACT FROM AUTHOR]