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Wearable sensing solutions have emerged as a promising paradigm for monitoring human musculoskeletal state in an unobtrusive way. To increase the deployability of these systems, considerations related to cost reduction and enhanced form factor and wearability tend to discourage the number of sensors in use. In our previous work, we provided a theoretical solution to the problem of jointly reconstructing the entire muscular-kinematic state of the upper limb, when only a limited amount of optimally retrieved sensory data are available. However, the effective implementation of these methods in a physical, under-sensorized wearable has never been attempted before. In this work, we propose to bridge this gap by presenting an under-sensorized system based on inertial measurement units (IMUs) and surface electromyography (sEMG) electrodes for the reconstruction of the upper limb musculoskeletal state, focusing on the minimization of the sensors' number. We found that, relying on two IMUs only and eight sEMG sensors, we can conjointly reconstruct all 17 degrees of freedom (five joints, twelve muscles) of the upper limb musculoskeletal state, yielding a median normalized RMS error of 8.5% on the non-measured joints and 2.5% on the non-measured muscles.

Background: Human-likeliness of robot movements is a key component to enable a safe and effective human-robot interaction, since it contributes to increase acceptance and motion predictability of robots that have to closely interact with people, e.g. for assistance and rehabilitation purposes. Several parameters have been used to quantify how much a robot behaves like a human, which encompass aspects related to both the robot appearance and motion. The latter point is fundamental to allow the operator to interpret robotic actions, and plan a meaningful reactions. While different approaches have been presented in literature, which aim at devising bio-aware control guidelines, a direct implementation of human actions for robot planning is not straightforward, still representing an open issue in robotics., Methods: We propose to embed a synergistic representation of human movements for robot motion generation. To do this, we recorded human upper-limb motions during daily living activities. We used functional Principal Component Analysis (fPCA) to extract principal motion patterns. We then formulated the planning problem by optimizing the weights of a reduced set of these components. For free-motions, our planning method results into a closed form solution which uses only one principal component. In case of obstacles, a numerical routine is proposed, incrementally enrolling principal components until the problem is solved with a suitable precision., Results: Results of fPCA show that more than 80% of the observed variance can be explained by only three functional components. The application of our method to different meaningful movements, with and without obstacles, show that our approach is able to generate complex motions with a very reduced number of functional components. We show that the first synergy alone accounts for the 96% of cost reduction and that three components are able to achieve a satisfactory motion reconstruction in all the considered cases., Conclusions: In this work we moved from the analysis of human movements via fPCA characterization to the design of a novel human-like motion generation algorithm able to generate, efficiently and with a reduced set of basis elements, several complex movements in free space, both in free motion and in case of obstacle avoidance tasks.

In this paper, we present a novel approach to dynamically describe human upper limb trajectories, addressing the question on whether and to which extent synergistic multi-joint behavior is observed and preserved over time evolution and across subjects. To this goal, we performed experiments to collect human upper limb joint angle trajectories and organized them in a dataset of daily living tasks. We then characterized the upper limb poses at each time frame through a technique that we named repeated-principal component analysis (R-PCA). We found that, although there is no strong evidence on the predominance of one principal component (PC) over the others, the subspace identified by the first three PCs takes into account most of the motion variability. We evaluated the stability of these results over time, showing that during the reaching phase, there is a strong consistency of these findings across participants. In other words, our results suggest that there is a time-invariant low-dimensional approximation of upper limb kinematics, which can be used to define a suitable reduced dimensionality control space for upper limb robotic devices in motion phases.

The accurate assessment of upper limb motion impairment induced by stroke - which represents one of the primary causes of disability world-wide - is the first step to successfully monitor and guide patients' recovery. As of today, the majority of the procedures relies on clinical scales, which are mostly based on ordinal scaling, operator-dependent, and subject to floor and ceiling effects. In this work, we intend to overcome these limitations by proposing a novel approach to analytically evaluate the level of pathological movement coupling, based on the quantification of movement complexity. To this goal, we consider the variations of functional Principal Components applied to the reconstruction of joint angle trajectories of the upper limb during daily living task execution, and compared these variations between two conditions, i.e. the affected and non-affected arm. A Dissimilarity Index, which codifies the severity of the upper limb motor impairment with respect to the movement complexity of the non-affected arm, is then proposed. This methodology was validated as a proof of concept upon a set of four chronic stroke subjects with mild to moderate arm and hand impairments. As a first step, we evaluated whether the derived outcomes differentiate between the two conditions upon the whole data-set. Secondly, we exploited this concept to discern between different subjects and impairment levels. Results show that: i) differences in terms of movement variability between the affected and nonaffected upper limb are detectable and ii) different impairment profiles can be characterized for single subjects using the proposed approach. Although provisional, these results are very promising and suggest this approach as a basis ingredient for the definition of a novel, operator-independent, sensitive, intuitive and widely applicable scale for the evaluation of upper limb motion impairment.

The Electroencephalogram (EEG) can be considered as the output of a nonlinear system whose dynamics is significantly affected by motor tasks. Nevertheless, computational approaches derived from the complex system theory has not been fully exploited for characterising motor imagery tasks. To this extent, in this study we investigated EEG complexity changes throughout the following categories of imaginary motor tasks of the upper limb: transitive (actions involving an object), intransitive (meaningful gestures that do not include the use of objects), and tool-mediated (actions using an object to interact with another one). EEG irregularity was quantified following the definition of Fuzzy Entropy, which has been demonstrated to be a reliable quantifier of system complexity with low dependence on data length. Experimental results from paired statistical analyses revealed minor topographical changes between EEG complexity associated with transitive and tool-mediated tasks, whereas major significant differences were shown between the intransitive actions vs. the others. Our results suggest that EEG complexity level during motor imagery tasks of the upper limb are strongly biased by the presence of an object.