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1. Predictive variables of spontaneous micturition recovery after acute urinary retention in men with benign prostatic enlargement: An observational prospective study.

Author

Vella M, Abrate A, Costanzo A, D'Amato F, Tarantino ML, and Simonato A

Subjects
Acute Disease, Aged, Area Under Curve, C-Reactive Protein metabolism, Humans, Male, Middle Aged, Organ Size, Prospective Studies, Prostatic Hyperplasia pathology, ROC Curve, Severity of Illness Index, Urinary Catheterization, Urinary Retention etiology, Prostate pathology, Prostatic Hyperplasia complications, Recovery of Function, Urinary Retention physiopathology, Urinary Retention therapy, Urination
Abstract

Objective: Acute urinary retention (AUR) is the sudden and painful inability to urinate spontaneously. AUR is one of the most significant complications of benign prostatic enlargement. The management of AUR is based on transurethral catheterization. Subsequent therapy is uncertain, but AUR seems to benefit from the use of alpha-blockers. The aim of this study was to evaluate the variables that could predict which patients would recover spontaneous micturition after trial without catheter., Methods: The present prospective observational study included men with AUR in an Italian tertiary care institute in 2016. Patients were catheterized and treated orally with fluoroquinolones, alpha-blockers, and Serenoa repens extracts. Preoperative variables as age, C-reactive protein (CRP), previous prostate-specific antigen values, urinary retention volume, prostate volume, and scores on a modified International Prostate Symptom Score questionnaire (IPSS-4), were investigated in relation to spontaneous micturition recovery., Results: Mean (±SD) age was 68.4 ± 7.1 years. Spontaneous and valid micturition recovery was observed in 11 patients (29.7%), whereas 26 (70.3%) needed to be catheterized again. The IPSS-4 score was significantly lower (9 vs 17; P < .001) and CRP values were significantly higher (43.00 vs 1.00 mg/dL; P < .001) in patients who recovered spontaneous micturition. The IPSS-4 scores and CRP showed an area under the curve of 0.85 and 0.87, respectively. for the prediction of spontaneous and valid micturition recovery., Conclusion: CRP and IPSS-4 could be useful tools to predict spontaneous micturition recovery after catheterization associated with medical therapy for AUR., (© 2018 John Wiley & Sons Australia, Ltd.)

Published
2019
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2. Predictive variables of spontaneous micturition recovery after acute urinary retention in men with benign prostatic enlargement: An observational prospective study

Author

ML Tarantino, Francesco D'Amato, Angela Costanzo, Alchiede Simonato, Marco Vella, Alberto Abrate, Vella, Marco, Abrate, Alberto, Costanzo, Angela, D'Amato, Francesco, Tarantino, Maria L., and Simonato, Alchiede

Subjects
Male, medicine.medical_specialty, Neurology, media_common.quotation_subject, Urology, 030232 urology & nephrology, Prostatic Hyperplasia, Urination, Severity of Illness Index, C-reactive protein, 03 medical and health sciences, 0302 clinical medicine, Prostate, medicine, Humans, Prospective Studies, acute urinary retention, Prospective cohort study, media_common, Aged, spontaneous micturition recovery, International Prostate Symptom Score, biology, Urinary retention, business.industry, Area under the curve, Organ Size, Recovery of Function, Middle Aged, Urinary Retention, medicine.anatomical_structure, ROC Curve, 030220 oncology & carcinogenesis, Area Under Curve, Acute Disease, biology.protein, medicine.symptom, business, Urinary Catheterization
Abstract

Objective: Acute urinary retention (AUR) is the sudden and painful inability to urinate spontaneously. AUR is one of the most significant complications of benign prostatic enlargement. The management of AUR is based on transurethral catheterization. Subsequent therapy is uncertain, but AUR seems to benefit from the use of alpha-blockers. The aim of this study was to evaluate the variables that could predict which patients would recover spontaneous micturition after trial without catheter. Methods: The present prospective observational study included men with AUR in an Italian tertiary care institute in 2016. Patients were catheterized and treated orally with fluoroquinolones, alpha-blockers, and Serenoa repens extracts. Preoperative variables as age, C-reactive protein (CRP), previous prostate-specific antigen values, urinary retention volume, prostate volume, and scores on a modified International Prostate Symptom Score questionnaire (IPSS-4), were investigated in relation to spontaneous micturition recovery. Results: Mean (±SD) age was 68.4 ± 7.1 years. Spontaneous and valid micturition recovery was observed in 11 patients (29.7%), whereas 26 (70.3%) needed to be catheterized again. The IPSS-4 score was significantly lower (9 vs 17; P

Published
2018

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