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We evaluated erectile function in men born with classic bladder exstrophy using a validated instrument and compared results with those in age matched controls.A total of 28 patients born with bladder exstrophy were invited to self-administer an Italian version of the International Index of Erectile Function-15 to assess erectile and orgasmic function, sexual desire and satisfaction, and overall satisfaction. A score of 25 or less of 30 in the erectile function domain was considered diagnostic for erectile dysfunction. Scores in patients with bladder exstrophy were compared with scores in 38 normal controls who self-administered the same questionnaire.A total of 19 men (68%) with a median age of 27.1 years (range 18.3 to 41.2) returned the questionnaire, of whom 11 (58%) presented with erectile dysfunction compared to 9 (23%) age matched controls (p = 0.02). Erectile dysfunction was more common in patients with bladder exstrophy who underwent multiple continence surgeries. Orgasmic function was also significantly lower in patients with bladder exstrophy than in controls (p = 0.001). No difference was observed between the groups in the sexual desire, sexual satisfaction and overall satisfaction domains.Patients born with classic bladder exstrophy appear to have erectile dysfunction and decreased orgasmic function more commonly than normal controls, particularly when they underwent multiple continence surgeries. Sexual desire seems comparable to that of their peers. Eventually patients with bladder exstrophy seem to lead a sexual life that is as satisfactory as that of their peers.

We report the case of a renal cell carcinoma with solitary metastasis to the urinary bladder, occurring 3 years after radical nephrectomy in a 68-year-old patient. The cystoscopy revealed a solid and rounded bladder lesion with a fine footstalk. Transurethral resection was performed and the pathological diagnosis was of eosinophil cell and clear cell carcinoma. The patient also presented secondary lesions in under- and upper-diaphragmatic lymph node area, brain and lung; therefore, he received treatment with several systemic therapies (Sorafenib, Sutent, Everolimus, IFN-alpha, Oxaliplatin and Gemcitabine).

Objective To report long-term donor site outcome after mandibular labial mucosa graft (LMG) harvesting in children. Material and methods Donor site outcome was evaluated after a follow-up of at least 5 years in 30 patients ≤14 years of age at surgery undergoing mandibular LMG harvesting for urethral reconstruction. Outcome domains considered included intra-oral donor site scarring, alteration in salivary flow, peri-oral numbness and tightness of the mouth. Results After a median follow-up of 8 years (range 6–11.8 years), at a median age at evaluation of 13.4 years (range 9–22.2 years), 16 (53%) of the patients reported to feel a thickening at the harvesting site, none reported alterations in the salivary flow, and one patient each reported tightness of the mouth and peri-oral numbness. None of the patients reported symptoms to be bothersome enough to seek treatment. Conclusion LMG harvest is safe in children and associated with minimal long-term intra-oral symptoms.