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Your search keyword '"K, Ichinohe"' showing total 7 results
Start Over Author "K, Ichinohe" Topic uterine cervical neoplasms
7 results on '"K, Ichinohe"'

1. [Insufficiency fracture of the pelvis after the radiotherapy for carcinoma of the uterine cervix].

Author

Nishimura T, Shimizu T, Sugiyama A, Ichinohe K, Teshima T, Takahashi M, Takai M, and Kaneko M

Subjects
Aged, Carcinoma, Squamous Cell complications, Female, Fractures, Bone diagnostic imaging, Humans, Middle Aged, Pelvic Bones diagnostic imaging, Radionuclide Imaging, Tomography, X-Ray Computed, Uterine Cervical Neoplasms complications, Carcinoma, Squamous Cell radiotherapy, Fractures, Bone etiology, Pelvic Bones injuries, Radiotherapy adverse effects, Uterine Cervical Neoplasms radiotherapy
Abstract

Bone injury after the radiotherapy for carcinoma of the uterine cervix has been reported since early days of this century. Recently, the concept of insufficiency fracture has been confirmed. Insufficiency fracture is one of the stress fractures and occurs when the elastic resistance of bone is inadequate to withstand normal or physiological stress. In the American and European studies, radiotherapy is known as a cause of insufficiency fracture. There are no reports on insufficiency fracture in the Japanese literatures. Four cases of carcinomas of the uterine cervix presented pelvic insufficiency fractures following radiotherapy. In the public bone, a vertical para-symphyseal fracture with mixed lytic and sclerotic changes of surrounding tissue is characteristic. Sacral insufficiency fracture shows a vertical or horizontal line with lytic and sclerotic appearance. Bone scintigraphy is a sensitive modality for the early detection. H-shaped configuration is diagnostic for sacral insufficiency fracture. CT is an accurate technique demonstrating a vertical fracture and excluding the malignant bony lesion. Although radiological findings of insufficiency fracture are similar to bone malignancy, differential diagnosis from malignant lesions is possible. Bony symptoms of all patients disappeared without specific treatments. In the follow-up study of patients with carcinomas of the uterine cervix after radiotherapy, it is important to have the consideration on insufficiency fracture.

Published
1990

2. [Present status of mass screening of cancer of the uterine cervix].

Author

Kutsuzawa T, Moriya S, Okubo H, Sakuragi N, and Ichinohe K

Subjects
Adult, Aged, False Negative Reactions, Female, Humans, Japan, Middle Aged, Uterine Cervical Neoplasms mortality, Vaginal Smears, Mass Screening, Uterine Cervical Neoplasms epidemiology
Published
1986

3. Clinical evaluation of sizofiran combined with irradiation in patients with cervical cancer. A randomized controlled study; a five-year survival rate.

Author

Okamura K, Suzuki M, Chihara T, Fujiwara A, Fukuda T, Goto S, Ichinohe K, Jimi S, Kasamatsu T, and Kawai N

Subjects
Combined Modality Therapy, Female, Humans, Randomized Controlled Trials as Topic, Survival Rate, Time Factors, Uterine Cervical Neoplasms mortality, Uterine Cervical Neoplasms radiotherapy, Antineoplastic Agents therapeutic use, Glycosaminoglycans therapeutic use, Sizofiran therapeutic use, Uterine Cervical Neoplasms drug therapy
Abstract

Following a previous report we ascertained the effectiveness of sizofiran (Schizophyllan:SPG) to prolong the survival and time to recurrence of the patients with Stage II or III cervical cancer, as evaluated in a 5-year randomized controlled study conducted in 19 institutions in Japan. Of the overall patients with Stage II or III cancer, time to recurrence and survival rate in the group on SPG were significantly longer than in the control group. In the Stage II patients, there was significant difference in time to recurrence, and survival of SPG group tended to be longer than that of the control group. However, in the Stage III patients, there was no significant difference in either time to recurrence or survival rate.

Published
1989
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4. Clinical evaluation of schizophyllan combined with irradiation in patients with cervical cancer. A randomized controlled study.

Author

Okamura K, Suzuki M, Chihara T, Fujiwara A, Fukuda T, Goto S, Ichinohe K, Jimi S, Kasamatsu T, and Kawai N

Subjects
Actuarial Analysis, Aged, Combined Modality Therapy, Drug Administration Schedule, Drug Evaluation, Female, Humans, Leukocyte Count, Neoplasm Recurrence, Local, Neoplasm Staging, Radiotherapy Dosage, Random Allocation, Sizofiran adverse effects, Uterine Cervical Neoplasms pathology, Uterine Cervical Neoplasms radiotherapy, Glycosaminoglycans therapeutic use, Sizofiran therapeutic use, Uterine Cervical Neoplasms drug therapy
Abstract

To evaluate the clinical effects of the anti-tumor polysaccharide Schizophyllan (SPG), a randomized study was done on 220 patients with Stage II or Stage III cervical cancer who had been given irradiation, concomitantly. The tumor-reducing effect of SPG was significant in patients in either stage. The time to recurrence was longer in SPG-dosed patients with Stage II cancer, compared with findings in the control group. There was no significant difference in the time to recurrence in patients with Stage III cancer between the SPG and control groups. When comparing the 48-month survival curve, the survival time of patients with Stage II cancer in the SPG group was significantly longer than in the control group. However, there was no significant difference in the survival rate of patients with Stage III cancer between the SPG-dosed and control groups.

Published
1986
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5. [Insufficiency fracture of the pelvis after the radiotherapy for carcinoma of the uterine cervix]

Author

T, Nishimura, T, Shimizu, A, Sugiyama, K, Ichinohe, T, Teshima, M, Takahashi, M, Takai, and M, Kaneko

Subjects
Fractures, Bone, Radiotherapy, Carcinoma, Squamous Cell, Humans, Uterine Cervical Neoplasms, Female, Middle Aged, Pelvic Bones, Radionuclide Imaging, Tomography, X-Ray Computed, Aged
Abstract

Bone injury after the radiotherapy for carcinoma of the uterine cervix has been reported since early days of this century. Recently, the concept of insufficiency fracture has been confirmed. Insufficiency fracture is one of the stress fractures and occurs when the elastic resistance of bone is inadequate to withstand normal or physiological stress. In the American and European studies, radiotherapy is known as a cause of insufficiency fracture. There are no reports on insufficiency fracture in the Japanese literatures. Four cases of carcinomas of the uterine cervix presented pelvic insufficiency fractures following radiotherapy. In the public bone, a vertical para-symphyseal fracture with mixed lytic and sclerotic changes of surrounding tissue is characteristic. Sacral insufficiency fracture shows a vertical or horizontal line with lytic and sclerotic appearance. Bone scintigraphy is a sensitive modality for the early detection. H-shaped configuration is diagnostic for sacral insufficiency fracture. CT is an accurate technique demonstrating a vertical fracture and excluding the malignant bony lesion. Although radiological findings of insufficiency fracture are similar to bone malignancy, differential diagnosis from malignant lesions is possible. Bony symptoms of all patients disappeared without specific treatments. In the follow-up study of patients with carcinomas of the uterine cervix after radiotherapy, it is important to have the consideration on insufficiency fracture.

Published
1990

6. Clinical evaluation of schizophyllan combined with irradiation in patients with cervical cancer. A randomized controlled study

Author

K, Okamura, M, Suzuki, T, Chihara, A, Fujiwara, T, Fukuda, S, Goto, K, Ichinohe, S, Jimi, T, Kasamatsu, and N, Kawai

Subjects
Sizofiran, Uterine Cervical Neoplasms, Radiotherapy Dosage, Combined Modality Therapy, Drug Administration Schedule, Leukocyte Count, Random Allocation, Actuarial Analysis, Drug Evaluation, Humans, Female, Neoplasm Recurrence, Local, Aged, Glycosaminoglycans, Neoplasm Staging
Abstract

To evaluate the clinical effects of the anti-tumor polysaccharide Schizophyllan (SPG), a randomized study was done on 220 patients with Stage II or Stage III cervical cancer who had been given irradiation, concomitantly. The tumor-reducing effect of SPG was significant in patients in either stage. The time to recurrence was longer in SPG-dosed patients with Stage II cancer, compared with findings in the control group. There was no significant difference in the time to recurrence in patients with Stage III cancer between the SPG and control groups. When comparing the 48-month survival curve, the survival time of patients with Stage II cancer in the SPG group was significantly longer than in the control group. However, there was no significant difference in the survival rate of patients with Stage III cancer between the SPG-dosed and control groups.

Published
1986

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