4 results on '"Parlato, Antonino"'
Search Results
2. Persistence of immunity 18–19 years after vaccination against hepatitis B in 2 cohorts of vaccinees primed as infants or as adolescents in Italy
- Author
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Romanò, Luisa, Galli, Cristina, Tagliacarne, Catia, Tosti, Maria Elena, Velati, Claudio, Fomiatti, Laura, Chironna, Maria, Coppola, Rosa Cristina, Cuccia, Mario, Mangione, Rossana, Marrone, Fosca, Negrone, Francesco Saverio, Parlato, Antonino, Zotti, Carla Maria, Mele, Alfonso, Zanetti, Alessandro Remo, Spada, Enea, Alfonsi, Valeria, Sallustio, Anna, Procacci, Rossella, Masia, Giuseppina, Meloni, Angelo, Grande, Silvana Lo, Filippo, Cantone, Gonfalone, Vito, Consagra, Rosa Maria, Russotto, Angela, Frangapani, Domenico, Ulivieri, Giovanna, Nini, Alessandra, Maldini, Morena, Cafarelli, Giuseppe, Giambersio, Antonio, Alfieri, Rosa, Santolo, Milena Scotto di, Zamparo, Emanuela, Cacello, Elena, Montu’, Domenico, and Belloni, Annamaria
- Subjects
Male ,0301 basic medicine ,Secondary ,Pediatrics ,HBsAg ,Time Factors ,Booster dose ,immune memory ,Group A ,Group B ,0302 clinical medicine ,HBV ,Immunology and Allergy ,Medicine ,030212 general & internal medicine ,Young adult ,biology ,virus diseases ,Hepatitis B ,Research Papers ,Vaccination ,Italy ,Female ,Antibody ,long-term immunity ,hepatitis B ,vaccination ,Adolescent ,Adult ,Hepatitis B Antibodies ,Hepatitis B Vaccines ,Humans ,Infant ,Young Adult ,Immunization, Secondary ,Immunologic Memory ,Immunology ,Pharmacology ,medicine.medical_specialty ,030106 microbiology ,complex mixtures ,03 medical and health sciences ,Internal medicine ,business.industry ,medicine.disease ,digestive system diseases ,biology.protein ,Immunization ,business - Abstract
This study was aimed at assessing the anti-HBs persistence and immune memory 18–19 y after vaccination against hepatitis B in healthy individuals primed as infants or adolescents. We enrolled 405 teenagers (Group A) vaccinated as infants, and 409 young adults (Group B) vaccinated as adolescents. All vaccinees were tested for anti-HBs and anti-HBc antibodies; those found anti-HBc positive were further tested for HBsAg and HBV DNA. Eight individuals belonging to Group B were positive for anti-HBc alone, and were excluded from analysis. Individuals with anti-HBs concentration ≥ 10 mIU/ml were considered protected while those with anti-HBs concentration
- Published
- 2017
3. Compliance with herpes zoster vaccination in young and adult individuals in two regions of Italy.
- Author
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Parlato, Antonino, Spica, Vincenzo Romano, Ciccozzi, Massimo, Farchi, Francesca, Galle, Francesca, Onofrio, Valeria Di, Franco, Elisabetta, Liguori, Giorgio, Romano Spica, Vincenzo, Gallè, Francesca, and Di Onofrio, Valeria
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MEDICAL research , *HERPES zoster , *VARICELLA-zoster virus , *PREVENTIVE medicine , *VACCINATION - Abstract
Background: The purpose of this work was to explore the knowledge and acceptance of Varicella Zoster Virus (VZV)-Herpes Zoster (HZ) vaccination in the general Italian population, where the HZ vaccine has not yet been distributed, using a prevalence study of subjects from two regions in Italy.Methods: A group of 3,173 individuals were interviewed using a questionnaire. The youngest age group (or= 41 years) were interviewed by general practitioners in their office. Results: In both regions, the majority of subjects had been infected with varicella, and only 165 (5.2%) subjects reported receiving the VZV vaccination. Regarding HZ, 2,749 (86.6%) individuals stated that they knew of the virus and 2,233 (70%) were willing to be vaccinated against HZ. The majority of people willing to be vaccinated were in the middle and older age groups (36.6% and 44.7%, respectively).Conclusion: Compliance versus vaccination results were satisfactory and probably, with the upcoming availability of the HZ vaccine in Italy, adults will be favourably disposed towards vaccination. [ABSTRACT FROM AUTHOR]- Published
- 2010
- Full Text
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4. Long-term immunogenicity of hepatitis B vaccination and policy for booster: an Italian multicentre study.
- Author
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Zanetti, Alessandro Remo, Mariano, Andrea, Romano, Luisa, D'Amelio, Raffaele, Chironna, Maria, Coppola, Rosa Cristina, Cuccia, Mario, Mangione, Rossana, Marrone, Fosca, Negrone, Francesco Saverio, Parlato, Antonino, Zamparo, Emanuela, Zotti, Carla, Stroffolini, Tommaso, and Mele, Alfonso
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IMMUNIZATION , *IMMUNIZATION of children , *HEPATITIS , *VACCINATION , *PREVENTION of communicable diseases , *PREVENTIVE medicine , *CLINICAL trials - Abstract
Summary Background Universal anti-hepatitis-B vaccination of infants and adolescents was implemented in Italy in 1991. We undertook a multicentre study in previously vaccinated individuals to assess the duration of immunity and need for booster, over 10 years after vaccination. Methods In 1212 children and 446 Italian Air Force recruits vaccinated as infants and adolescents, respectively, we measured the concentrations of antibodies to hepatitis-B surface antigen (anti-HBs) and the presence of antibodies to hepatitis-B core antigen (anti-HBc) at enrolment; postimmunisation values were not available. Individuals positive for anti-HBc were tested for hepatitis B surface antigen (HBsAg) and hepatitis B viral DNA. Individuals with anti-HBs concentrations at 10 IU/L or more were regarded as protected; those with antibody less than 10 IU/L were given a booster dose and retested 2 weeks later. Individuals showing postbooster anti-HBs concentrations of less than 10 IU/L were offered two additional vaccine doses and retested 1 month after the third dose. Findings Protective anti-HBs concentrations were retained in 779 (64%, 95% CI 61·6-67) children and 398 (89%, 86·4-92·1) recruits. We recorded antibody amounts of less than 10 IU/L in 433 children (36%, 33-38·4) and 48 (11%, 7·9-13·6) recruits. One child and four recruits were positive for anti-HBc, but negative for HBsAg and hepatitis B viral DNA. Antibody concentrations were higher in recruits than in children (geometric mean titre 234·8 IU/L vs 32·1 IU/L, p=0·0001). 332 (97%) of 342 children and 46 (96%) of 48 recruits who received a booster showed an anamnestic response, whereas ten (3%) children and two (4%) recruits remained negative for anti-HBs or had antibody concentrations of less than 10 IU/L. Prebooster and postbooster antibody titres were strongly correlated with each other in both groups. All individuals given two additional vaccine doses (eight children and two recruits) showed anti-HBs amounts of more than 10 IU/L at 1 month after vaccination. Interpretation Strong immunological memory persists more than 10 years after immunisation of infants and adolescents with a primary course of vaccination. Booster doses of vaccine do not seem necessary to ensure long-term protection. [ABSTRACT FROM AUTHOR]
- Published
- 2005
- Full Text
- View/download PDF
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