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Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: HIV-infected children have a higher risk of presenting infections, including the hepatitis A virus (HAV). The inactivated HAV vaccine is immunogenic in immunocompetent hosts; however, there are insufficient studies on the duration of seroprotection in HIV-infected children. Methods: An analytical cohort study was conducted. HIV-1-infected children who received the inactivated HAV vaccine (2 doses) were included. Blood samples were taken for antibody measurement, the first one 28 days after the second dose and another 7 years after the vaccination schedule. Information on viral load, immunological category, weight, height, and response to antiretroviral treatment from diagnosis to the last assessment was obtained. Results: 19 patients were included, with a mean age of 12.6 years (SD ± 2.29). 58% were male. 80% of the patients presented protective immunoglobulin G antibodies against HAV 7-year post-vaccination. The antibody concentration was found to be between 13 and 80 mIU/mL (median of 80 mIU/mL). 52% showed some degree of immunosuppression. There was no statistically significant relationship between the presence of seroprotection and viral load, treatment failure, immunological category, and malnutrition. Twelve patients presented with antiretroviral treatment failure, and in 33% of them, the antibodies did not offer satisfactory seroprotection. Conclusion: 7-year post-vaccination, 80% of HIV-infected children maintain seroprotection titers against HAV. [ABSTRACT FROM AUTHOR]

Copyright of Gaceta Médica de Caracas is the property of Academia Nacional de Medicina and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Image patterns at the vaccination site and lymph node drainage provide us with useful information about the immune response due to the recent introduction of the coronavirus disease 2019 (COVID-19) vaccine. These findings are visualized as lymph node reactivity with increased radiotracer uptake in positron emission tomography (PET) studies with 18 fluorodeoxyglucose. However, from another point of view, the phenomenon of recent vaccination may represent a new diagnostic challenge when carrying out an interpretation. We present the case of a health worker, who was requested a PET/CT as a diagnostic complement for low back pain under study. [ABSTRACT FROM AUTHOR]

Copyright of Revista Comunicação Midiática is the property of Universidade Estadual Paulista, Faculdade de Arquitetura, Artes e Comunicacao and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Comunicação Midiática is the property of Universidade Estadual Paulista, Faculdade de Arquitetura, Artes e Comunicacao and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Some theories suggest that the development of the immune response to clear hepatitis B triggers the intestinal tissue damage seen in celiac disease in genetically predisposed individuals. Although the role of hepatitis B virus infection in the development of autoimmune diseases has been widely discussed in the literature, it remains a controversial topic. Our objective is to review whether there is an association between hepatitis B and celiac disease and the particularities of vaccination against hepatitis B in celiac patients. [ABSTRACT FROM AUTHOR]

Copyright of Medicina y Seguridad del Trabajo is the property of Escuela Nacional de Medicina del Trabajo - Instituto de Salud Carlos III and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Cuadernos.info is the property of Pontificia Universidad Catolica de Chile, Facultad de Comunicaciones and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Habanera de Ciencias Médicas is the property of Universidad de Ciencias Medicas de La Habana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Enfermagem Brasil is the property of Atlantica Editora and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Vaccines are an essential public health resource for disease containment and reduction of associated mortality rates. With the emergence of COVID-19, public debates on the themes of vaccines and vaccination processes became important topics on diverse media and social networking platforms. In this article, our objective was to identify and reflect on the emotions evoked in the Brazilian public with respect to the COVID-19 vaccine during 2020 and 2021 on Facebook. To achieve this, we used the Crowdtangle graphical interface to extract complete copies of posts made by public Facebook profiles during this timeframe, from which a random sample of 1,067 posts was selected for analysis. Identification of emotions was performed using the Human-Machine Interaction Network on Emotion (HUMAINE) descriptors as a baseline reference. Emotions were then grouped into categories following Core Affect Model guidelines. Data analysis and interpretation indicated a prevalence of positive emotions such as trust, interest, and hope directed toward vaccines in the Brazilian domestic scenario. Negative emotions such as worry and disapproval were also expressed, albeit in reference to contextual issues (for example, the spread of COVID-19, delays in vaccine access, and the emergence of new variants) and public figures, such as the President of Brazil. [ABSTRACT FROM AUTHOR]

Copyright of Comunicar (English Edition) is the property of Oxbridge Publishing House and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de Enfermagem e Atenção à Saúde (REAS) is the property of Revista de Enfermagem e Atencao a Saude - Reas and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

With the discovery of COVID-19 (SARS-CoV-2) at the end of 2019, science denial ensures its continuity through new demands like the emergence and the containment methods of the virus, as well as the effectiveness of vaccines in the path towards eradicating the new disease. Relying on false narratives that, like COVID-19 itself, have manifested spatially in a heterogeneous manner around the globe, primarily in those countries where conservatism, characterized by the extreme right-wing, was in power. In response to this phenomenon, this research aims to provoke some reflections on the contributions that critical geography can make in combating denial and its manifestation against vaccines. This considers the importance of mass vaccination and its social impacts, as well as the full exercise of autonomy guaranteed by the use of truth and science. For this purpose, this exploratory research will employ Historical Dialectical Materialism as its method, seeking to minimize the impacts of this phenomenon rooted in the perverse globalization and reinforce the role of geographical science. The ultimate goal is to provide considerations for decision-making in the social, political, and economic spheres regarding these challenges. [ABSTRACT FROM AUTHOR]

BACKGROUND: As the vaccination campaign expands worldwide, skin reactions caused by SARS-CoV-2 and its vaccines have been described. Lichenoid reaction is an inflammatory autoimmune disease that can be associated with infections, medications, and vaccinations. Recently, there have been reports of cases occurring after the administration of the mRNA-based SARS-CoV-2 vaccine, particularly the Pfizer/BioNTech vaccine. CLINICAL CASE: A 37-year-old female patient, healthy, who started three days after the application of her second dose of the vaccine against SARS-CoV-2 from the manufacturer AstraZeneca, with a dermatosis that affected upper and lower extremity, constituted by multiple papules of reddish color that settled on the red ink of his tattoos, well defined, flat topped and itchy. The clinical appearance of the rash and histopathology confirmed the lichenoid reaction diagnosis. The skin lesions responded well to treatment with topical steroids and oral antihistamines. CONCLUSIONS: The lichenoid reaction in tattoos has a good prognosis because with topical therapy it successfully remits, its possible association with vaccination against SARS-CoV-2 does not represent a reason to discourage vaccination against a virus that is potentially deadly. [ABSTRACT FROM AUTHOR]

Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Medica Colombiana is the property of Acta Medica Colombiana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of ESPOCH Congresses: The Ecuadorian Journal of S.T.E.A.M. is the property of Knowledge E DMCC and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Salud, Ciencia y Tecnología is the property of Fundacion Salud, Ciencia y Tecnologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of QhaliKay: Revista de Ciencias de la Salud is the property of QhaliKay Revista de Ciencias de la Salud and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Global Security & Intelligence Studies is the property of Policy Studies Organization and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: vaccines against COVID-19 have already proven their efficacy, but their effectiveness is still unknown. Objective: to determine the effectiveness of the different vaccines in health personnel to prevent COVID-19. Material and methods: cohort study. All health personnel vaccinated against SARS-CoV-2 and who treated patients with COVID-19 were considered and compared with unvaccinated health personnel. Were questioned about the diagnosis of COVID-19 corroborated by PCR or antigen testing, and its complications. Statistical analysis: for the determination of effectiveness, the formula: EV = (1 - OR) × 100. Results: 340 health workers were studied; 325 vaccinated and 15 unvaccinated. Of 325 vaccinated with the first dose, 8 were positive for SARS-CoV-2, second dose, 35 of 286 and booster in 272, 50 tested positive, 4 of 15 unvaccinated tested positive. The effectiveness for the first dose was 97.5%, the second 95.2% and the booster 9.91%. Conclusions: the effectiveness of the vaccine against mild COVID-19 in health personnel vaccinated in the first dose is high, it decreases a little for the 2nd dose but drops dramatically for the booster to only 9.91%. [ABSTRACT FROM AUTHOR]

Copyright of Ecosistemas y Recursos Agropecuarios is the property of Universidad Juarez Autonoma de Tabasco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Cystic echinococcosis (CE) is a zoonosis caused by species of the complex Echinococcus granulosus, sensu lato in their larval stage. It is an endemic disease in the province of Río Negro, where lamb vaccination with EG95 was incorporated in 2009 with very good results: in fact, it contributed to a significant drop in prevalence of infection in diverse hosts. However, impact studies have revealed the need to improve understanding of local epidemiology. The objective was to identify causes which can still generate infection in dogs. In indigenous reserves comprised within the area of lamb vaccination with 3 doses of EG95, prevalence in adult caprines and ovines was determined by necropsy and serology (ELISA). Through serology, infection rates in vaccinated and non-vaccinated ovines were significantly different (p= 0.0004), as well as between non-vaccinated ovines and goats (p= 0.0013); on the other hand, infection rate differences between vaccinated sheep and non-vaccinated goats turned out non-significant (p= 0.254). Through necropsy, such difference between vaccinated and non-vaccinated ovines turned out significant (p= 0.0016); between non-vaccinated ovines and non-vaccinated goats, it proved non-significant (p= 0.23). With reference to epidemiology and control along the period 2018-2022, vaccination strategy was maintained, and 2 extra deworming tasks were introduced, performed by the vaccination team. Assessment of animal slaughter for consumption in 41 producers showed that 21 of them slaughter a monthly average of 18 goats, and 36 in all slaughter 35 old sheep. Design and implementation of programme resulted cost-effective, since it was possible to maintain them over time, with clear impact on prevalence decrease in diverse hosts. [ABSTRACT FROM AUTHOR]

This paper tries to analyse the conscientious objection of two NBA basketball players to receiving the Covid-19 vaccine on religious grounds. Essentially, the aim is to examine in depth the reasons alleged by the athletes, in an attempt to determine whether they constitute sufficient grounds to support their refusal to be vaccinated, and thus to continue carrying out their work obligations in order to preserve their beliefs. To do so, it is necessary to review the NBA's own protocols and state and local public health provisions on mandatory vaccination, without forgetting the pronouncements on the subject issued by the Supreme Court of the United States. [ABSTRACT FROM AUTHOR]

Myocarditis is a multifactorial inflammatory condition of the myocardium. Recently myocarditis has been recognized as an adverse event in patients vaccinated against COVID-19 with Pfizer-BioNTech and Moderna (mRNA vaccines), mainly in adolescents and young adults. Cardiac magnetic resonance (CMR) allows the characterization of myocardial tissue and cardiac function and has become the non-invasive diagnostic gold standard in patients with suspected acute myocarditis. The authors present a 16-year-old male case with stabbing chest pain after the second dose of immunization against SARS-CoV-2 with the BNT162B2 (Pfizer-BioNTech) vaccine. The electrocardiogram (ECG) showed disclosed ST-segment elevation, and increased myocardial injury markers were also observed. Angio tomography (AngioCT) showed subtle signs of myocardial hypoperfusion and left ventricular dysfunction. Gadolinium CMR was performed, identifying global hypokinesis of the left ventricle (LV), myocardial edema hyperemia and late gadolinium enhancement (LGE) as evidence of myocardial injury, and markers of non-ischemic intramyocardial inflammatory lesion. Having excluded other etiologies, this presentation of acute myocarditis is proposed to be an adverse reaction associated with the BNT162b2 vaccine against COVID-19. The long-term risks of the COVID-19 vaccine in children, adolescents and young adults are still unknown, and further investigation will be needed. [ABSTRACT FROM AUTHOR]

New aspects emerged in the dynamics of international politics, not only globally, but in different regions of the world, after the emergence of the COVID-19 pandemic. This article aims to characterize the use of vaccines by India and Russia as a diplomatic tool over their regions of traditional influence: South and Central Asia. The research makes use of the case study methodology and is based on primary and secondary sources, between August 2020 and November 2021. Russia is intensifying its presence in Central Asia, where its vaccine has greater roots and acceptance, and India is regaining its influence in neighboring countries such as Nepal and Sri Lanka. While they seek to improve their regional prestige, their actions counteract China's growing interference in these two regions. The benefits of these two Asian middle powers are concentrated in an increase in their international prestige, trade opportunities, as counterweight to China; in addition to influencing the decisions of other countries, who waver between an aligned and multivector foreign policy. [ABSTRACT FROM AUTHOR]

Copyright of Revista Estomatología is the property of Universidad del Valle and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Apuntes Universitarios: Revista de Investigación is the property of Universidad Peruana Union Filiar Tarapoto and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Dimensión Empresarial is the property of Universidad Autonoma del Caribe, Departamento del Atlantico and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Elaborar recomendaciones para la prevención de infección en pacientes adultos con enfermedades reumáticas autoinmunes sistémicas (ERAS). Un panel de expertos, seleccionados con base en su currículum y experiencia, identificó preguntas clínicas de investigación relevantes para el objetivo del documento. Se realizaron revisiones sistemáticas de la evidencia, que se graduó de acuerdo con los criterios del Scottish Intercollegiate Guidelines Network. Tras ello, se formularon las recomendaciones. Se seleccionaron cinco preguntas, referentes a la prevención de infección por Pneumocystis jirovecii con trimetoprim-sulfametoxazol, medidas profilácticas contra el virus de la hepatitis B, vacunación contra el virus del papiloma humano, vacunación contra el Streptococcus pneumoniae y vacunación contra el virus de la gripe. Se formularon un total de 18 recomendaciones, estructuradas por pregunta, con base en la evidencia encontrada para las diferentes ERAS y/o consenso de expertos. Existe suficiente evidencia sobre la seguridad y eficacia de las vacunaciones y otras medidas profilácticas frente a los microrganismos revisados en este documento como para ser recomendadas específicamente en pacientes con ERAS. To develop recommendations for the prevention of infection in adult patients with systemic autoimmune rheumatic diseases (SARD). Clinical research questions relevant to the objective of the document were identified by a panel of experts selected based on their experience in the field. Systematic reviews of the available evidence were conducted, and evidence was graded according to the Scottish Intercollegiate Guidelines Network criteria. Specific recommendations were made. Five questions were selected, referring to prevention of infection by Pneumocystis jirovecii with trimethoprim/sulfamethoxazole, primary and secondary prophylactic measures against hepatitis B virus, vaccination against human papillomavirus, vaccination against Streptococcus pneumoniae and vaccination against influenza virus, making a total of 18 recommendations, structured by question, based on the evidence found for the different SARD and/or expert consensus. There is enough evidence on the safety and efficacy of vaccinations and other prophylactic measures against the microorganisms reviewed in this document to specifically recommend them for patients with SARD. [ABSTRACT FROM AUTHOR]

Copyright of Cirugía y Cirujanos is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The COVID-19 pandemic is a global public health problem that has revealed deficiencies and challenges in health systems worldwide. To date, four waves (each one driven by different viral variants and showing different behaviors) have affected Mexico. Here we describe the COVID-19 pandemic behavior in the population of Sinaloa, Mexico after four epidemic waves. Epidemiological data were obtained from public federal databases from March 2020 to February 2022, and genomes of SARS-CoV-2 variants of interest (VOI) and concern (VOC) in Sinaloa were downloaded from the GISAID database from January 2021 to May 2022. The relative risk (RR) of SARS-CoV-2 infection was calculated from public data. Sinaloa presented four epidemic waves from March 2020 to February 2022, and each wave was driven by different variants with different degrees of transmissibility and severity. Interestingly, the delta variant (which dominated the third wave) was probably the most severe, producing a large number of cases per day and high mortality rates, while the omicron variant (which dominated the fourth wave) produced the largest number of cases per day but decreased mortality rates. Most of the COVID-19 cases in Sinaloa occurred among people between 30 and 45 years old, and the average age of the deceased was above 60 years old in all waves. Older people showed higher risk of infection than infants and younger people; however, the relative risk (RR) for people older than 60 years old decreased in the third and fourth waves. Men older than 60 years old showed higher RR than women of the same age group. The COVID-19 pandemic has shown changing behaviors in time, mostly derived from different emerging viral variants and the immunization of the population. Overall, these results show that SARS-CoV-2 infections appear in timely waves, each one driven by different variants (and subvariants or sublineages), with different degrees of transmissibility and severity. The population should continue with preventive measures to avoid infection. [ABSTRACT FROM AUTHOR]

Introduction. Monkey pox is a zoonotic infection with an increased global transmission rate during 2022, denoted epidemiological trouble in public health. Currently, the disease has no specific treatments available; thus, a preventive approach can be achieved through immunization. Objective. was to design in silico a vaccine applying advanced computational techniques using a multi-epitope construct of the Monkeypox virus. Materials and methods. Antigens were selected based on reports about proteins that cause the activation of cytotoxic T and B lymphocytes. The immunoinformatics assays were antigenicity, allergenicity, toxicity, MHC binding affinity, and IFN-γ stimulation. Results and discussion. Eight epitopes of the M1R, DNA polymerase, B6R, and A35R proteins of the M. virus showed a significant response for immune cells. Eleven epitopes with antigenicity >0.3, non-allergenic and non-toxic were chosen, of which 4 presented high affinity to T lymphocytes, 4 generated high activation of B lymphocytes, and 3 were associated with IFN-γ activation results. The in silico construction of the 509-amino acid vaccine candidate with high topological similarity registered mainly a negative charge, in addition to being soluble with an aliphatic index >80%, stable and particular with MHC activation and high molecular affinity with TLR-3, and also presented multi-antigenicity, similar to vaccines generated by this methodology with M. tuberculosis and Influenza. One-dose injection simulation of the molecular construct showed activation of T helper plasma cells for about 15 to 25 days and high expression of IFN-γ and IL-2 for eight days. Conclusion. These results indicate an excellent immunization process that could be potentiated with multi-dosing. [ABSTRACT FROM AUTHOR]

Introduction: The human papilloma virus (HPV) is the leading cause of cervical cancer. Having an instrument that measures the acceptance of the HPV vaccine, as well as the factors involved in the acceptance process, is an urgent need for HPV prevention. The objective was to validate the knowledge, beliefs, and acceptance of the human papillomavirus vaccine instrument. Materials and Methods: The validation process was carried out through a descriptive, cross-sectional study and a two-phase process. The population consisted of 393 mothers of girls between the ages of 9 and 11 years, belonging to the State of Puebla, with a non-probabilistic sampling for convenience; the sample was considered at a ratio of 10: 1. Results: A valid and reliable instrument was obtained with a Cronbach's Alpha of .70, a value of p <.000 for Bartlett's sphericity test, and .82 for the KMO test. In this sense, the factor analysis resulted in a total of 40 items divided into six dimensions. Discussion: The methodological process allowed to have an empirical indicator adapted and validated for the Mexican context, since it is the only one within the context that measures the factors related to the acceptance of the HPV vaccine. Conclusion: We conclude that having an empirical indicator adapted to the Spanish language, which measures acceptance and related factors, is a contribution of great importance to society and an advance in nursing science. [ABSTRACT FROM AUTHOR]

Copyright of Acta Medica Colombiana is the property of Acta Medica Colombiana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Salud, Ciencia y Tecnología is the property of Fundacion Salud, Ciencia y Tecnologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The mortality rate estimated by the WHO worldwide for CO- VID-19 has been 5.7%, much higher than other communicable infectious diseases, so it is essential to apply a vaccine to the population to reduce the viral spread, according to the WHO there are 23 projects in clinical phase stage III, such as vaccines: ChadOx1, nCov-19, Gam-COVID-Vac, CoronaVac that show promising results in research published by The Lancet Infection Diseases journal, for which we consider correlating the three vaccines and determining which is safer, generates greater immunogenicity and less reactogenicity in volunteer participants, for which we conducted a review bibliography and a meta-analysis of high impact scientific articles, concluding that the three vaccines generate a rapid and intense immune response against SARS-CoV-2, neutralizing antibodies had elevated titers in participants at 28 days, who increased and remained stable with a second dose, although each of them have been tested in different numbers and populations, applying recombinant adenoviral vectors and chemically inactivated virions with adjuvant and placebo for which they are totally different but with the same purpose to generate memory antibodies against SARS-CoV-2. [ABSTRACT FROM AUTHOR]

Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Question (1669-6581) is the property of Universidad Nacional de La Plata and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Ciencias de la Salud is the property of Colegio Mayor de Nuestra Senora del Rosario and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)