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Your search keyword '"Zhao-yang Qin"' showing total 2 results
Start Over Author "Zhao-yang Qin" Topic vascular endothelial growth factor
2 results on '"Zhao-yang Qin"'

1. Cyclooxygenase-2 expression and its association with vascular endothelial growth factor, microvessel density and clinicopathologic characteristics of colorectal carcinoma

Author

Zhao-Yang Qin, Xiao-Yan Guo, Jing-Zhong Xu, and Gang-Ping Wang

Subjects
Colorectal carcinoma, Cyclooxygenase-2 expression, Micorvessel density, Vascular endothelial growth factor, Therapeutics. Pharmacology, RM1-950
Abstract

The aim of this study was to investigate the expression of cyclooxygenase type-2 (COX-2) and its association with angiogenesis and clinicopathologic characteristics of colorectal carcinoma (CRC). COX-2 expression was detected by means of immunohistochemistry in a series of human tissue samples with CRC (n = 120), dysplasia tissue closely adjacent to carcinomas (n = 40) and normal colorectal mucosa (n = 40), and their expressions association with vascular endothelial growth factor (VEGF), CD31-labeled micorvessel density(MVD) in CRC and other clinicopathologic characteristics were investigated. The expression of COX-2 in CRC tissues (78.3%) was obviously higher than that in adjacent tissue and normal mucosal tissue (p

Published
2016

2. Cyclooxygenase-2 expression and its association with vascular endothelial growth factor, microvessel density and clinicopathologic characteristics of colorectal carcinoma

Author

Jing-Zhong Xu, Xiao-Yan Guo, Zhao-Yang Qin, and Gang-Ping Wang

Subjects
0301 basic medicine, Pathology, medicine.medical_specialty, Colorectal cancer, Angiogenesis, Micorvessel density, Biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Grading (tumors), Microvessel density, Pharmacology, Colorectal carcinoma, Cyclooxygenase-2 expression, Vascular endothelial growth factor, lcsh:RM1-950, medicine.disease, digestive system diseases, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, chemistry, Dysplasia, 030220 oncology & carcinogenesis, biology.protein, Immunohistochemistry, Cyclooxygenase
Abstract

The aim of this study was to investigate the expression of cyclooxygenase type-2 (COX-2) and its association with angiogenesis and clinicopathologic characteristics of colorectal carcinoma (CRC). COX-2 expression was detected by means of immunohistochemistry in a series of human tissue samples with CRC (n = 120), dysplasia tissue closely adjacent to carcinomas (n = 40) and normal colorectal mucosa (n = 40), and their expressions association with vascular endothelial growth factor (VEGF), CD31-labeled micorvessel density(MVD) in CRC and other clinicopathologic characteristics were investigated. The expression of COX-2 in CRC tissues (78.3%) was obviously higher than that in adjacent tissue and normal mucosal tissue (p

Published
2016

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