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Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Angiogenesis and osteogenesis are essential parts of bone development. The regeneration and angiogenic-osteogenic coupling exist through the whole process of bone formation and remodeling, which play important roles in the mechanisms such as new bone formation, fracture healing, bone defect repair, and osteoporosis. Vascular endothelial cells, vascular endothelial growth factors, and other factors are key parts in angiogenic-osteogenic coupling. Especially in recent years, the discovery of specific H-type blood vessel enriches the content of vascular-osteogenesis coupling and deepens the understanding of the coupling. Blood vessels and bones are closely related and interacted with each other. The significances of blood vessels to bones are not only the transmission of bone-transferring substances, but also the secretion of factors, signal transmission, function regulation, and so on. Bone related cells can secrete or promote the secretion of vascular endothelial growth factor and other angiogenic factors, which regulate angiogenesis. Therefore, this present paper summarizes the role of angiogenic-osteogenic coupling-related factors, cells, and their mechanisms in the bone. [ABSTRACT FROM AUTHOR]