1. Vitamin D in pediatric health and disease.
- Author
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Peroni DG, Trambusti I, Di Cicco ME, and Nuzzi G
- Subjects
- Autoimmunity, Child, Humans, Vitamin D immunology, Ascorbic Acid Deficiency immunology, Asthma metabolism, Dermatitis, Atopic metabolism, Inflammation metabolism, Respiratory Tract Infections metabolism, T-Lymphocytes, Regulatory immunology, Vitamin D metabolism
- Abstract
Several scientific societies established that vitamin D (VD), in its metabolized form 25(OH)D, levels higher than 20 ng/mL are sufficient to ensure optimal bone health, while 25(OH)D levels higher than 30 ng/mL are needed to favor VD extraskeletal actions. However, it has been estimated that approximately 30% of children and 60% of adults worldwide are VD deficient and insufficient, respectively. This is the reason why it is important to provide a practical approach to VD supplementation for infants, children, and adolescents. It is the pediatrician's role to evaluate the modifiable lifestyle risk factors for deficiency, particularly a reduced sun exposure, following an evidence-based approach, and to suggest VD supplementation only when there is a rational reason to support its use., (© 2020 EAACI and John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
- Published
- 2020
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