1. Progress on production of succinic acid by Actinobacillus succinogenes – New opportunities for cheap biomass and waste gas utilization.
- Author
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Yang, Yan, Zhao, Junxiong, Zhou, Ying, Xu, Shengchao, Ren, Xiulian, and Wei, Qifeng
- Subjects
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SUCCINIC acid , *WASTE recycling , *WASTE gases , *BIOCONVERSION , *ACTINOBACILLUS , *ATMOSPHERIC carbon dioxide , *ENERGY crops , *LIGNOCELLULOSE - Abstract
Succinic acid is an important basic raw material and intermediate used in chemical, pharmaceutical, food and agricultural fields. Due to the dual pressure of oil crisis and environmental pollution of the chemical process, the biosynthesis of succinic acid through microbial fermentation has been given much attention. In particular, the bioconversion of succinic acid from CO 2 and inexpensive biomass by Actinobacillus succinogenes can reduce production costs, mitigate dependence on petroleum for specialty chemical production and lower the atmospheric CO 2 concentration, thereby alleviating environmental problems. This review summarizes the new trends in the production of succinic acid by A. succinogenes. We start by introducing the unique and promising functions of A. succinogenes as a natural succinic acid producer. We then focus on the progress, challenges and future prospects of using energy crops, lignocellulosic biomass, solid waste and waste gases to produce succinic acid. Process optimization during the utilization of cheap biomass and waste gas is also highlighted. We pay particular attention to the currently known and potential promising methods to deal with the fermentation inhibitors which affects the bio-based succinic acid production. Lastly, the breeding strategies for efficient construction of A. succinogenes strains are discussed. [Display omitted] • Actinobacillus succinogenes , a succinic acid producer, may contribute to carbon-neutrality and zero-waste strategies. • Utilization of cheap and renewable carbon sources reduces production and environmental costs of bio-succinic acid. • The breeding objective of A. succinogenes should be more closely integrated with cheap biomass and waste gas utilization. • Combining directional and non-directional breeding techniques will be beneficial to increase the yield of succinic acid. • State-of-the-art techniques for converting solid wastes into value-added products in laboratory scale have been reviewed. [ABSTRACT FROM AUTHOR] more...
- Published
- 2024
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