1. Functional Mapping of the Human Visual Cortex with Intravoxel Incoherent Motion MRI.
- Author
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Federau, Christian, O’Brien, Kieran, Birbaumer, Adrien, Meuli, Reto, Hagmann, Patric, and Maeder, Philippe
- Subjects
BRAIN mapping ,DIFFUSION magnetic resonance imaging ,VISUAL cortex ,ECHO-planar imaging ,CEREBROSPINAL fluid ,WHITE matter (Nerve tissue) - Abstract
Functional imaging with intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) is demonstrated. Images were acquired at 3 Tesla using a standard Stejskal-Tanner diffusion-weighted echo-planar imaging sequence with multiple b-values. Cerebro-spinal fluid signal, which is highly incoherent, was suppressed with an inversion recovery preparation pulse. IVIM microvascular perfusion parameters were calculated according to a two-compartment (vascular and non-vascular) diffusion model. The results obtained in 8 healthy human volunteers during visual stimulation are presented. The IVIM blood flow related parameter fD* increased 170% during stimulation in the visual cortex, and 70% in the underlying white matter. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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