1. Potential role of dengue virus, chikungunya virus and Zika virus in neurological diseases.
- Author
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Vieira MADCES, Costa CHN, Linhares ADC, Borba AS, Henriques DF, Silva EVPD, Tavares FN, Batista FMA, Guimarães HCL, Martins LC, Monteiro TAF, Cruz ACR, Azevedo RDSDS, and Vasconcelos PFDC
- Subjects
- Acute Disease, Encephalitis diagnosis, Encephalitis virology, Encephalomyelitis, Acute Disseminated diagnosis, Encephalomyelitis, Acute Disseminated virology, Enzyme-Linked Immunospot Assay, Guillain-Barre Syndrome diagnosis, Guillain-Barre Syndrome virology, Humans, Myelitis, Transverse diagnosis, Myelitis, Transverse virology, Nervous System Diseases diagnosis, Reverse Transcriptase Polymerase Chain Reaction, Chikungunya virus genetics, Chikungunya virus immunology, Dengue Virus genetics, Dengue Virus immunology, Nervous System Diseases virology, Zika Virus genetics, Zika Virus immunology
- Abstract
This study showed that laboratory markers of recent infection by dengue, Zika or chikungunya arboviruses were detected in the biological samples of approximately one-third of patients with encephalitis, myelitis, encephalomyelitis or Guillain-Barré syndrome, in a surveillance programme in Piauí state, Brazil, between 2015-2016. Fever and myalgia had been associated with these cases. Since in non-tropical countries most infections or parainfectious diseases associated with the nervous system are attributed to herpesviruses, enteroviruses, and Campylobacter jejuni, the present findings indicate that in tropical countries, arboviruses may now play a more important role and reinforce the need for their surveillance and systematic investigation in the tropics.
- Published
- 2018
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