1. Administration of Brincidofovir and Convalescent Plasma in a Patient With Ebola Virus Disease.
- Author
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Florescu DF, Kalil AC, Hewlett AL, Schuh AJ, Stroher U, Uyeki TM, and Smith PW
- Subjects
- Adult, Africa, Western, Alanine Transaminase blood, Antibodies, Viral blood, Aspartate Aminotransferases blood, Bilirubin blood, Cytosine administration & dosage, Humans, Immunoglobulin G blood, Immunoglobulin M blood, Leukocyte Count, Male, Platelet Count, RNA, Viral blood, Randomized Controlled Trials as Topic, Treatment Outcome, Viral Load, Antiviral Agents administration & dosage, Cytosine analogs & derivatives, Hemorrhagic Fever, Ebola therapy, Immunization, Passive, Organophosphonates administration & dosage, Plasma
- Abstract
From 2014 to May 2015, >26 000 Ebola virus disease (EVD) cases were reported from West Africa. We present a patient with EVD who received brincidofovir and convalescent plasma. The relative contributions of supportive care, investigational therapies, and patient's immune-response on survival could not be determined. Randomized trials are needed., (© The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2015
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