4 results on '"Sahil"'
Search Results
2. The Global Extent of Undetected Glaucoma in Adults: A Systematic Review and Meta-analysis.
- Author
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Soh, Zhi, Yu, Marco, Betzler, Bjorn Kaijun, Majithia, Shivani, Thakur, Sahil, Tham, Yih Chung, Wong, Tien Yin, Aung, Tin, Friedman, David S., and Cheng, Ching-Yu
- Subjects
- *
OPEN-angle glaucoma , *ANGLE-closure glaucoma , *GLAUCOMA , *HUMAN Development Index , *ONLINE databases , *GREY literature - Abstract
Glaucoma is the leading cause of irreversible blindness, despite having good prognosis with early treatment. We evaluated the global extent of undetected glaucoma and the factors associated with it in this systematic review and meta-analysis. Undetected glaucoma increases the risk of vision impairment, which leads to detrimental effects on the quality-of-life and socioeconomic well-being of those affected. Detailed information on the extent and factors associated with undetected glaucoma aid in the development of public health interventions. We conducted a systematic review and meta-analysis of population-based studies published between January 1, 1990, and June 1, 2020. Article search was conducted in online databases (PubMED, Web-of-Science), grey literatures (OpenGrey), and nongovernment organization reports. Our outcome measure was the proportion of glaucoma cases that were undetected previously. Manifest glaucoma included any form of glaucoma reported in the original studies and may include primary open-angle glaucoma (POAG), primary angle-closure-glaucoma, secondary glaucoma, or a combination thereof. Undetected glaucoma was defined as glaucoma cases that were undetected prior to diagnosis in the respective study. Random-effect meta-analysis was used to estimate the pooled proportion of undetected glaucoma. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and the Meta-analysis of Observational Studies in Epidemiology guidelines in our study. We identified 61 articles from 55 population-based studies (n = 189 359 participants; n = 6949 manifest glaucoma). Globally, more than half of all glaucoma cases were undetected previously on average in each geographical region. Africa (odds ratio [OR], 12.70; 95% confidence interval [CI], 4.91–32.86) and Asia (OR, 3.41; 95% CI, 1.63–7.16) showed higher odds of undetected glaucoma as compared with Europe. Countries with low Human Development Index (HDI; <0.55) showed a higher proportion of undetected manifest glaucoma as compared with countries of medium to very high HDI (≥0.55; all P < 0.001). In 2020, 43.78 million POAG cases were projected to be undetected, of which 76.7% were in Africa and Asia. Undetected glaucoma is highly prevalent across diverse communities worldwide and more common in Africa and Asia. Strategies to improve detection are needed to prevent excess visual disability and blindness resulting from glaucoma. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
3. Establishing African genomics and bioinformatics programs through annual regional workshops.
- Author
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Sharaf A, Nesengani LT, Hayah I, Kuja JO, Mdyogolo S, Omotoriogun TC, Odogwu BA, Beedessee G, Smith RM, Barakat A, Moila AM, El Hamouchi A, Benkahla A, Boukteb A, Elmouhtadi A, Mafwila AL, Abushady AM, Elsherif AK, Ahmed B, Wairuri C, Ndiribe CC, Ebuzome C, Kinnear CJ, Ndlovu DF, Iraqi D, El Fahime E, Assefa E, Ouardi F, Belharfi FZ, Tmimi FZ, Markey FB, Radouani F, Zeukeng F, Mvumbi GL, Ganesan H, Hanachi M, Nigussie H, Charoute H, Benamri I, Mkedder I, Haddadi I, Meftah-Kadmiri I, Mubiru JF, Domelevo Entfellner JK, Rokani JB, Ogwang J, Daiga JB, Omumbo J, Ideozu JE, Errafii K, Labuschagne K, Komi KK, Tonfack LB, Hadjeras L, Ramantswana M, Chaisi M, Botes MW, Kilian M, Kvas M, Melloul M, Chaouch M, Khyatti M, Abdo M, Phasha-Muchemenye M, Hijri M, Mediouni MR, Hassan MA, Piro M, Mwale M, Maaloum M, Mavhunga M, Olivier NA, Aminou O, Arbani O, Souiai O, Djocgoue PF, Mentag R, Zipfel RD, Tata RB, Megnekou R, Muzemil S, Paez S, Salifu SP, Kagame SP, Selka S, Edwards S, Gaouar SBS, Reda SRA, Fellahi S, Khayi S, Ayed S, Madisha T, Sahil T, Udensi OU, Ras V, Ezebuiro V, Duru VC, David X, Geberemichael Y, Tchiechoua YH, Mungloo-Dilmohamud Z, Chen Z, Happi C, Kariuki T, Ziyomo C, Djikeng A, Badaoui B, Mapholi N, Muigai A, Osuji JO, and Ebenezer TE
- Subjects
- Africa, Humans, Biodiversity, Genomics education, Computational Biology methods, Computational Biology education
- Abstract
The African BioGenome Project (AfricaBP) Open Institute for Genomics and Bioinformatics aims to overcome barriers to capacity building through its distributed African regional workshops and prioritizes the exchange of grassroots knowledge and innovation in biodiversity genomics and bioinformatics. In 2023, we implemented 28 workshops on biodiversity genomics and bioinformatics, covering 11 African countries across the 5 African geographical regions. These regional workshops trained 408 African scientists in hands-on molecular biology, genomics and bioinformatics techniques as well as the ethical, legal and social issues associated with acquiring genetic resources. Here, we discuss the implementation of transformative strategies, such as expanding the regional workshop model of AfricaBP to involve multiple countries, institutions and partners, including the proposed creation of an African digital database with sequence information relating to both biodiversity and agriculture. This will ultimately help create a critical mass of skilled genomics and bioinformatics scientists across Africa., (© 2024. Springer Nature America, Inc.)
- Published
- 2024
- Full Text
- View/download PDF
4. Recurrent Oral Ulcers in a Refugee.
- Author
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Mullick S, Pan YF, Desai A, Singh S, and Ekong E
- Subjects
- Adult, Africa ethnology, Chronic Disease, Diagnosis, Differential, Humans, Male, Microscopy, Fluorescence, Mouth Mucosa pathology, Oral Ulcer ethnology, Oral Ulcer etiology, Pemphigus diagnosis, Pemphigus ethnology, Recurrence, United States epidemiology, Oral Ulcer diagnosis, Pemphigus complications, Refugees
- Published
- 2018
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