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The article focuses on the problems AIDS fighters in various African countries are finding while trying to get African men circumcised in an effort to prevent AIDS and the transmission of AIDS. Many of the countries have a severe shortage of doctors, patients who are minimally educated, and minimal medical regulations, which has resulted in many African men receiving their circumcisions at illegal locations and having them done by barely medically educated medical staff.

Profiles Anne Bayley, who first identified the presence of AIDS in Zambia. Career highlights, including how she came to Zambia as a British missionary doctor in 1961; History of the disease's spread in Africa; Patients treated by Bayley at her tumor clinic for Kaposi's sarcoma (KS), whom she recognized as having AIDS; How the association of AIDS with homosexuality greatly inhibited scientific understanding of the disease's transmission; Bayley's contributions to AIDS research; Her personal views on AIDS.

Discusses the effort of Glaxo Wellcome PLC to block competition for its anti-AIDS drug Combivir in Ghana. Comments from Christopher Kiige of the African Regional Industrial Property Organization; HIV infections in sub-Saharan Africa; Agreement on pricing among pharmaceutical companies.