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Objective: Health literacy improves self-regulation and management of diabetes through proper diets in diabetic men. As a result, they will gain more knowledge about the effects of this disease on marital life and sexual relationships. The present study aimed to investigate the relationship between women's marital intimacy with sexual satisfaction and health literacy among husbands with diabetes. Materials and Methods: The method of the present research was descriptive and correlational. The statistical population of the study included all male patients with diabetes and their wives in Ahvaz in 2021. Convenience sampling was done to select 140 diabetic men with their wives as the research sample. The research instruments included the Intimacy Questionnaire in Marital Relationships, the Index of Sexual Satisfaction, and Health Literacy for Iranian Adults. Pearson's correlation coefficient and simultaneous regression analysis were used for data analysis. Results: According to the results, sexual satisfaction and health literacy in diabetic men had significant positive relationships with the women's marital intimacy (P< 0.001). Furthermore, regression results indicated that sexual satisfaction and health literacy had significant multiple correlations with marital intimacy (P< 0.001). Conclusion: The results highlighted the growing importance of paying attention to the roles of women's sexual satisfaction and their diabetic husbands' health literacy in improving marital intimacy and strengthening both family and marital relationships. [ABSTRACT FROM AUTHOR]