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Purpose: The aim of this paper is to raise awareness within built environment and associated disciplines regarding the potential for initiating and triggering events associated with chemical sensitivity as a result of chemical treatments used for the control or eradication of fungal infections and/or insect infestations in buildings. Design: Literature review and interviews with affected individuals. Materials and methods: The information has been obtained by literature search and review of published sources from built environment and associated disciplines; also from personal communications with those affected by chemical treatments and treatment residues in buildings. Results: Chemical treatments used for the control or eradication of fungal infections and/or insect infestations in buildings and the residues of such treatments do not pose a proven hazard to the general population. There is, however, an apparent potential risk from such treatments and from the presence of treatment residues in treated buildings for persons who suffer from chemical sensitivity. Conclusions: Based on a review of published information and personal communications, it is concluded that further investigation and evaluation is required of alternative chemical and non-chemical treatments of fungal infections and/or insect infestations in buildings. In addition, further investigation and evaluation is required of techniques of containment of chemical treatment residues within treated building fabric and decontamination of treated buildings and personal belongings. There is also a need for improved awareness of health issues relating to the maintenance and management of buildings, and improved education of the general public and their professional advisers in relation to the potential hazards and risks associated with chemical treatments and treatment residues. Where risk assessments cannot adequately take account of the potential effects of chemical treatments and treatment residues in buildings, a precautionary approach should be adopted by those responsible for managing or implementing such works. [ABSTRACT FROM AUTHOR]