1. Escherichia coli O157:H7 vaccine field trial in 9 feedlots in Alberta and Saskatchewan.
- Author
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Van Donkersgoed J, Hancock D, Rogan D, and Potter AA
- Subjects
- Alberta, Animals, Cattle, Colony Count, Microbial veterinary, Escherichia coli Infections prevention & control, Escherichia coli O157 isolation & purification, Random Allocation, Saskatchewan, Bacterial Vaccines standards, Cattle Diseases prevention & control, Escherichia coli Infections veterinary, Escherichia coli O157 immunology, Feces microbiology
- Abstract
A feedlot trial was conducted to assess the efficacy of an Escherichia coli O157:H7 vaccine in reducing fecal shedding of E. coli O157:H7 in 218 pens of feedlot cattle in 9 feedlots in Alberta and Saskatchewan. Pens of cattle were vaccinated once at arrival processing and again at reimplanting with either the E. coli O157:H7 vaccine or a placebo. The E. coli O157:H7 vaccine included 50 microg of type III secreted proteins. Fecal samples were collected from 30 fresh manure patties within each feedlot pen at arrival processing, revaccination at reimplanting, and within 2 wk of slaughter. The mean pen prevalence of E. coli O157:H7 in feces was 5.0%; ranging in pens from 0% to 90%, and varying significantly (P < 0.001) among feedlots. There was no significant association (P > 0.20) between vaccination and pen prevalence of fecal E. coli O157:H7 following initial vaccination, at reimplanting, or prior to slaughter.
- Published
- 2005