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A recent study conducted at Aalborg University in Denmark explored the impact of chronic pain on the use-dependent plasticity of the motor cortex in musicians. The researchers used transcranial magnetic stimulation to assess corticospinal excitability in pain-free musicians, chronic pain musicians, and pain-free non-musicians. The study found that long-term musical training can lead to specialized functional organization of the primary motor cortex, and this adaptive plasticity is not significantly compromised by chronic pain. These findings suggest that long-term sensorimotor training may counteract the effects of chronic pain in the motor system. [Extracted from the article]