Search

Your search keyword '"Yahyaoui M"' showing total 1 results
Start Over Author "Yahyaoui M" Region algeria

Refine your results

1 results on '"Yahyaoui M"'

1. Linkage analysis of families with severe childhood autosomal recessive muscular dystrophy in Morocco indicates genetic homogeneity of the disease in north Africa.

Author

el Kerch F, Sefiani A, Azibi K, Boutaleb N, Yahyaoui M, Bentahila A, Vinet MC, Leturcq F, Bachner L, and Beckmann J

Subjects
Algeria, Child, Chromosomes, Human, Pair 13, Consanguinity, Female, Humans, Lod Score, Male, Morocco epidemiology, Muscular Dystrophies epidemiology, Pedigree, Sarcoglycans, Tunisia, Cytoskeletal Proteins genetics, Genes, Recessive, Membrane Glycoproteins genetics, Muscular Dystrophies ethnology, Muscular Dystrophies genetics
Abstract

It has been previously shown in Tunisian and Algerian families that the locus for SCARMD maps to the proximal part of 13q, and in Algerian families that the disease is associated with deficiency of the 50 kDa dystrophin associated glycoprotein (50DAG). We have tested this linkage in six families from Morocco where this disease is also prevalent. In one family the 50DAG was tested and found to be negative in a muscle biopsy. Our results showed similar linkage in this country, with statistical tests indicating genetic homogeneity between the three Maghreb countries.

Published
1994
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results