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1. The effect of autonomic blockers on heart rate: a comparison between two ethnic groups.

Author

Meyer EC, Sommers DK, Schoeman HS, and Avenant JC

Subjects
Adrenergic beta-Antagonists pharmacology, Adult, Angola, Atropine pharmacology, Black People, Electrocardiography, Ethnicity, Humans, Male, Single-Blind Method, South Africa, White People, Autonomic Agents pharmacology, Heart Rate drug effects
Abstract

The influence of autonomic blockers on the heart rate of ten Bushmen and eight White volunteers was studied. There were significant differences in heart rate response to atropine alone between the White's and Bushmen. However, after prior beta-adrenoceptor blockade, these differences were no longer significant. It is postulated that a varying pharmacogenetic sensitivity to autonomic blockers may result from inequality of vagal or sympathetic tone.

Published
1990
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