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Forgiveness, a construct common to religiousness/spirituality and positive psychology, and resentment are thought to be critical factors in addiction and recovery therefrom. Although empirical evidence is accumulating to support forgiveness as an important factor in addiction recovery, very little work has empirically examined the role of resentment in addiction recovery, including the role of the forgiveness – resentment interface. The association of forgiveness with addiction recovery-related outcomes, as mediated by resentment, in the context of substance (mis)use was examined in two cross-sectional studies among undergraduate college students from three institutions, in this IRB-approved study. Self-forgiveness was consistently associated – both directly and indirectly through resentment – with less psychological distress and less vulnerability to use substances in the context of both alcohol (mis)use and drug (mis)use. Other-forgiveness was similarly associated, but less frequently. Empirical evidence is beginning to emerge to support the long-held anecdotal assumptions regarding the importance of forgiveness and resentment to addiction recovery, with implications for interventions and approaches to treatment for those struggling with substance (mis)use. [ABSTRACT FROM AUTHOR]